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Whole Mitochondrial Genome NGS Panel, EDTA Blood**
₹ 14000
Whole Mitochondrial Genome Sequencing
₹ 14000 ₹ 14000

Whole Mitochondrial Genome Sequencing

Sample Type 51+ booked in last 3 days
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Whole Mitochondrial Genome NGS Panel, EDTA Blood** Price

₹ 14000

Brief Details

Preparation
No special preparation required
Also Known As
Whole Mitochondrial Genome NGS Panel, Mitochondrial DNA Sequencing
Fasting
Not required
Reporting Time
After 4 weeks
Purpose
Aids in diagnosing mitochondrial disorders and genetic syndromes, supports assessment of inherited metabolic disorders

What is a Whole Mitochondrial Genome Sequencing Test? 

A whole mitochondrial genome sequencing test is an advanced genetic test that examines the complete DNA sequence of the mitochondria in your body's cells. Mitochondria are often called the "powerhouses" of the cell because they generate most of the energy needed for your organs to function properly. 

This test helps diagnose or rule out mitochondrial diseases, which are a group of genetic disorders caused by changes in the mitochondrial DNA. 

What does the Whole Mitochondrial Genome Sequencing Test measure? 

The test specifically measures and identifies several key aspects of your mitochondrial DNA: 

  • Genetic variants (mutations): It reads the entire sequence of the 37 genes in mitochondrial DNA to find any changes that could be causing health problems 
  • Heteroplasmy levels: It measures the percentage of mutated DNA compared to normal DNA in your sample 
  • Large deletions or duplications: It detects if large pieces of mitochondrial DNA are missing or have been copied extra times 
  • Complete mitochondrial genome coverage: Ensures all areas of the mitochondrial DNA are examined thoroughly 

Whole Mitochondrial Genome Sequencing Test: Who Needs It and Why It's Done 

What Symptoms May Call for a Whole Mitochondrial Genome Sequencing Test? 

Doctors may recommend this test when you show a complex pattern of symptoms affecting multiple organ systems, especially those that require a lot of energy: 

  • Muscle problems: Unexplained muscle weakness, pain, low muscle tone, or difficulty with exercise 
  • Neurological Disorders: Developmental delays, seizures, stroke-like episodes, dementia, and movement disorders 
  • Heart problems: Weakening of the heart muscle or abnormal heart rhythms 
  • Vision and hearing: Vision loss, drooping eyelids, difficulty moving the eyes, and hearing problems 
  • Other symptoms: Diabetes, kidney problems, digestive issues, and unexplained fatigue 

Who should get a Whole Mitochondrial Genome Sequencing Test? 

This specialised test is recommended for specific groups of people: 

  • Patients with unexplained symptoms: Individuals from infants to adults who show a combination of the symptoms listed above without a clear diagnosis 
  • People with family history: Those who have a close relative diagnosed with a known mitochondrial disease 
  • Patients with atypical disease presentation: When symptoms don't fit a common disease pattern and a mitochondrial disorder might be the underlying cause 

Why is a Whole Mitochondrial Genome Sequencing Test done? 

This test provides a definitive genetic diagnosis for suspected mitochondrial disease, helping to end a long diagnostic journey and guide proper medical management and treatment planning. 

Importance of a Whole Mitochondrial Genome Sequencing Test 

The whole mitochondrial genome sequencing test is clinically important as one of the most comprehensive methods for diagnosing inherited mitochondrial disorders. It provides a definitive diagnosis that can pinpoint the exact genetic cause of your symptoms, which may have been unexplained for years. A specific diagnosis helps doctors manage the condition effectively through targeted treatments, vitamin supplements, dietary recommendations, and monitoring for potential complications.  

The test also enables accurate genetic counselling for you and your family, helping you understand inheritance patterns and risks for other family members or future children. 

Whole Mitochondrial Genome Sequencing Test Booking & Reports – Metropolis Healthcare India 

How to Book a Whole Mitochondrial Genome Sequencing Test? 

  1. Simple Online Booking 
    Booking can be done through the Metropolis Healthcare app or website. Select Whole Mitochondrial Genome Sequencing Test, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. 
     
  2. Safe Home Sample Collection 
    Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols. 
     
  3. Sample Tracking Updates 
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. 
     
  4. Accurate Laboratory Testing 
    Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results. 
     
  5. Quick & Easy Reports 
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app. 

Is home sample collection for Whole Mitochondrial Genome Sequencing Test available near you? 

Yes, home blood sample collection is available for the whole mitochondrial genome sequencing test. Our trained phlebotomists follow strict safety protocols while collecting your blood sample and processing it in NABL & CAP accredited labs. With our extensive network of over 10,000 touchpoints, our reliable home collection services ensure you receive accurate results without compromising on quality or convenience.  

How Long Does It Take to Get a Whole Mitochondrial Genome Sequencing Test Report? 

Reports are usually available after 4 weeks by 6:00 PM once the sample reaches the pathology lab. 

Note: Reporting time may vary depending on your location. 

Where can I see or get Whole Mitochondrial Genome Sequencing Test results? 

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare app to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab. 

Interpreting Whole Mitochondrial Genome Sequencing Test Results 

What Your Whole Mitochondrial Genome Sequencing Test Results May Indicate 

The table below explains the different types of results you may receive from your whole mitochondrial genome sequencing test: 

Result Type 

Classification 

Meaning 

Pathogenic Variant 

Disease-causing 

A genetic change known to cause mitochondrial disease has been identified 

Likely Pathogenic 

Very likely disease-causing 

A variant that probably contributes to disease, but needs more scientific evidence 

Variant of Uncertain Significance (VUS) 

Unknown significance 

A genetic change found, but unclear if it causes disease or is harmless 

No Variant Detected 

Normal/Negative 

No known disease-causing mutations were found in the mitochondrial DNA 

Conditions that May Affect Whole Mitochondrial Genome Sequencing Test Accuracy 

Several factors should be considered when interpreting your whole mitochondrial genome sequencing test results: 

  • Sample quality: Haemolysed, clotted, or insufficient blood samples can affect the accuracy of genetic analysis 
  • Laboratory conditions: Improper sample storage temperature or handling may impact DNA quality 
  • Technical limitations: Some genetic variations may not be detected by the specific sequencing method used 
  • Heteroplasmy levels: The percentage of mutated mitochondrial DNA in different tissues may vary 
  • Recent blood transfusions: May temporarily affect the genetic profile of red blood cells, WBS, or platelets in your blood sample 

How is a Whole Mitochondrial Genome Sequencing Test Done? 

The whole mitochondrial genome sequencing test follows a systematic laboratory process to analyse your mitochondrial DNA: 

  • A healthcare professional draws 3-5 ml of blood from a vein in your arm using an EDTA tube 
  • Laboratory technicians extract mitochondrial DNA from your blood cells 
  • The entire mitochondrial genome is selectively amplified using specialised techniques 
  • DNA is prepared for sequencing using advanced molecular biology methods 
  • The sample is sequenced on high-tech platforms to achieve comprehensive coverage 
  • Sophisticated software aligns and compares your DNA sequence to reference genomes 
  • Expert geneticists analyse the findings and prepare your detailed report 

How Should You Prepare for a Whole Mitochondrial Genome Sequencing Test? 

Preparing for your whole mitochondrial genome sequencing test is straightforward and requires minimal preparation: 

  • You can eat and drink normally before the test 
  • Take all prescribed medicines unless your doctor advises otherwise 
  • Drink adequate water to make the blood draw easier 
  • Choose clothes that allow easy access to your arm 
  • Ensure you have your doctor's prescription and clinical history 
  • Tell your healthcare provider about all medicines and supplements you're taking 

Diseases that a Whole Mitochondrial Genome Sequencing Test Can Help Detect 

The whole mitochondrial genome sequencing test can help diagnose various mitochondrial disorders and related health conditions: 

  • Leigh disease: A severe neurological disorder affecting the central nervous system 
  • MELAS syndrome: Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes 
  • MERRF syndrome: Myoclonic epilepsy with ragged red fibres 
  • Kearns-Sayre syndrome: A disorder affecting multiple body systems including eyes and heart 
  • Pearson syndrome: A severe multisystem disorder affecting bone marrow and pancreas 
  • Leber hereditary optic neuropathy: A condition causing vision loss 
  • Mitochondrial cardiomyopathy: Heart muscle disease caused by mitochondrial dysfunction 
  • Complex I, II, III, IV, or V deficiencies: Specific enzyme defects in the mitochondrial respiratory chain 

Whole Mitochondrial Genome Sequencing Test/Packages that You Can Book With Metropolis Healthcare 

Metropolis Healthcare offers comprehensive testing options to support your mitochondrial health assessment and genetic counselling needs: 

Test/Package Name 

Purpose/Highlights 

Genetics Counselling Test 

Professional guidance for understanding genetic test results and family planning 

Comprehensive Metabolic Panel 

Complete assessment of metabolic function including glucose, electrolytes, and kidney function 

Mitochondrial (M2) Antibody by IFA Reflex to Endpoint Titre Serum 

Detects autoimmune antibodies that may affect mitochondrial function 

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

Regular exercise, a balanced diet, avoiding smoking, maintaining a healthy weight, and managing stress all help reduce heart disease risk.

Common signs include irritability, trouble sleeping, headaches, difficulty concentrating, and muscle tension.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Choose precision On time, every time!

Precision
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  • Real-time tracking of phlebotomist arrival and report generation
  • Fully digital report delivery—view from mobile or desktop instantly
  • Continuous monitoring of turnaround times to ensure accuracy and speed
  • Dedicated support team to resolve any delays or queries quickly

Why Metropolis Healthcare?

Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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About Us

Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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