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Alport Syndrome
₹ 19400
Alport Syndrome Gene Panel by NGS Test
₹ 19400 ₹ 19400

Alport Syndrome Gene Panel by NGS Test

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Alport Syndrome Price

₹ 19400

Brief Details

Preparation
No special preparation required
Also Known As
Alport syndrome gene panel
Fasting
Fasting not required
Reporting Time
After 4 weeks
Purpose
To identify genetic mutations causing Alport syndrome and related hereditary kidney disorders

What is the Alport Syndrome Gene Panel by NGS Test?

The Alport Syndrome Gene Panel by NGS Test is a genetic blood test used to diagnose Alport syndrome, an inherited condition that affects the kidneys and can also involve hearing and vision. The disorder occurs due to defects in type IV collagen, an essential structural protein in the kidney filtration system.

This test analyses key genes associated with Alport syndrome using next generation sequencing technology. Identifying the exact genetic mutation helps confirm the diagnosis, determine the inheritance pattern, and support long-term kidney care and family counselling. The test requires a blood sample collected in an EDTA tube.

What Does the Alport Syndrome Gene Panel by NGS Test Measure?

This genetic test looks for disease-causing changes in collagen genes linked to Alport syndrome:

  • Detects pathogenic variants responsible for Alport syndrome
  • Helps distinguish Alport syndrome from other hereditary kidney disorders
  • Supports early diagnosis in individuals with unexplained blood or protein in urine
  • Aids genetic counselling and carrier screening in families
  • Guides long-term kidney disease monitoring and treatment planning

Alport Syndrome Gene Panel by NGS Test: Who Needs It and Why It’s Done

What Symptoms May Call for an Alport Syndrome Gene Panel by NGS Test?

Doctors may recommend this test if you or a family member show features suggestive of Alport syndrome, such as:

  • Persistent blood in urine detected on routine testing
  • Protein in urine with gradual decline in kidney function
  • Progressive hearing loss, especially in childhood or early adulthood
  • Eye abnormalities such as lens or retinal changes
  • Family history of kidney failure or hearing impairment

Who Should Get an Alport Syndrome Gene Panel by NGS Test?

This test may be advised for:

  • Individuals with suspected hereditary kidney disease
  • Children or adults with unexplained hematuria or proteinuria
  • Patients with kidney disease and hearing or vision problems
  • Families with a known history of Alport syndrome
  • Couples seeking genetic counselling before or during pregnancy

Why is the Alport Syndrome Gene Panel by NGS Test Done?

The test helps confirm a genetic diagnosis of Alport syndrome, allowing timely intervention to slow kidney damage and provide accurate counselling regarding disease progression and inheritance.

Alport Syndrome Gene Panel by NGS Test Booking & Reports – Metropolis Healthcare

How to Book the Alport Syndrome Gene Panel by NGS Test and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Alport Syndrome Gene Panel by NGS Test, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced molecular diagnostic technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Alport Syndrome Gene Panel by NGS Test Available Near You?

Yes, Metropolis Healthcare offers home sample collection for the Alport Syndrome Gene Panel by NGS Test. This service saves you time, reduces the need for travel, and ensures professional sample handling while maintaining strict quality standards.

In How Much Time Will I Get the Alport Syndrome Gene Panel by NGS Test Report?

Reports are usually available after 4 weeks once the sample reaches the lab.
Note: Reporting time may vary based on your location.

Where Can I See or Get Alport Syndrome Gene Panel by NGS Test Results?

You can access your test reports through the Metropolis Healthcare website or mobile app using your login credentials. Reports are also sent via email or WhatsApp, and you may collect a physical copy from the Metropolis Lab if required.

Interpreting Alport Syndrome Gene Panel by NGS Test Results

What Your Alport Syndrome Gene Panel Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
Alport syndrome related genes No disease causing variant detected Confirmed genetic Alport syndrome or related collagen disorder Symptoms may be due to non genetic causes or variants not detected by this panel

Understanding Abnormal Alport Syndrome Gene Panel Results by Gene Group

Gene Group What a Pathogenic Variant May Indicate
COL4A5 X linked Alport syndrome with higher risk of progressive kidney disease
COL4A3, COL4A4 Autosomal recessive or dominant Alport syndrome with variable severity

How Should You Prepare for an Alport Syndrome Gene Panel by NGS Test?

This genetic test requires minimal preparation from your side:

  • No fasting required: You can eat and drink normally before sample collection
  • Normal hydration: Maintain your usual fluid intake
  • Medication disclosure: Inform your doctor about any medicines or supplements you are taking
  • Share clinical history: Provide relevant medical and family history as advised
  • Consent and documentation: Ensure the test requisition form and genetic history details are completed

How Is an Alport Syndrome Gene Panel by NGS Test Done? (Step-by-Step Procedure)

The test is performed using a standard blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible
  • Cleaning: The puncture site is cleaned with antiseptic
  • Sample Collection: A sterile needle is used to draw about 3 to 5 ml of blood into an EDTA vacutainer
  • Completion: The needle is removed, and a bandage is applied
  • Processing: The sample undergoes next generation sequencing to analyse genes linked to Alport syndrome

Conditions That May Affect Alport Syndrome Gene Panel by NGS Test Accuracy

Certain patient related factors may influence test interpretation:

  • Recent blood transfusion, which may affect genetic analysis
  • Incomplete or inaccurate family history details
  • Presence of mosaic genetic changes that may require clinical correlation

Diseases That the Alport Syndrome Gene Panel by NGS Test Can Help Detect

  • Alport syndrome
  • Hereditary nephritis
  • Genetic collagen related kidney disorders
  • Inherited kidney disease with hearing involvement

References

  1. Kashtan C.E., Ding J., Gregory M., et al. (2013). Alport syndrome: A unified classification of genetic disorders of collagen IV. Kidney International, 83(5), 779–789. PMID: 23325009
  2. Savige J., Ariani F., Mari F., et al. (2016). Expert consensus guidelines for the genetic diagnosis of Alport syndrome. Pediatric Nephrology, 31(5), 639–648. PMID: 26234768
  3. Gross O., Licht C., Anders H.J., et al. (2012). Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure. Kidney International, 81(5), 494–501. PMID: 22166847

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

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Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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