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Neuronal migration disorder gene panel
₹ 19400
Neuronal Migration Disorder Gene Panel
₹ 19400 ₹ 19400

Neuronal Migration Disorder Gene Panel

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Neuronal migration disorder gene panel Price

₹ 19400

Brief Details

Preparation
No special preparation required
Also Known As
Neuronal migration disorder Gene Panel by NGS
Fasting
Fasting not required
Reporting Time
After 4 weeks
Purpose
To detect genetic mutations causing neuronal migration disorders and support diagnosis, management, and family risk assessment

What is the Neuronal Migration Disorder Gene Panel?

The Neuronal Migration Disorder Gene Panel is a genetic blood test used to identify inherited conditions that affect how nerve cells move and settle in the brain during early development. When this process is disrupted, it can lead to structural brain abnormalities and long term neurological problems.

This test analyses multiple genes associated with neuronal migration using advanced Next Generation Sequencing technology. It requires an EDTA blood sample and helps doctors confirm a genetic diagnosis, understand the underlying cause of brain malformations, and assess risks for other family members.

What Does the Neuronal Migration Disorder Gene Panel Measure?

This genetic test looks for disease causing changes in genes involved in brain development:

  • Detection of pathogenic variants linked to neuronal migration disorders
  • Identification of genetic causes of abnormal brain structure
  • Differentiation from other congenital or metabolic brain conditions
  • Support for diagnosis, prognosis assessment, and care planning
  • Guidance for genetic counselling, family screening, and prenatal evaluation

Neuronal Migration Disorder Gene Panel: Who Needs It and Why It’s Done

What Symptoms May Call for a Neuronal Migration Disorder Gene Panel?

Doctors may recommend this test if you or your child experience:

  • Developmental delay or intellectual disability
  • Seizures that begin in infancy or childhood
  • Abnormal brain findings on MRI or CT scans
  • Poor muscle tone or movement difficulties
  • Delayed milestones or regression of skills

Who Should Get a Neuronal Migration Disorder Gene Panel?

  • Children with suspected congenital brain malformations
  • Individuals with unexplained epilepsy and developmental delay
  • Patients with imaging findings suggestive of neuronal migration defects
  • Individuals with a family history of brain developmental disorders
  • Couples planning a pregnancy with known genetic risk

Why is a Neuronal Migration Disorder Gene Panel Done?

The test helps identify the genetic cause of neuronal migration disorders, enabling accurate diagnosis, targeted management, and informed counselling for affected individuals and their families.

Importance of the Neuronal Migration Disorder Gene Panel

Early genetic diagnosis of neuronal migration disorders provides clarity about the cause of neurological symptoms and helps guide long term care. This gene panel supports personalised management plans, anticipates potential complications such as epilepsy, and assists families with prognosis understanding and future reproductive planning.

Neuronal Migration Disorder Gene Panel Booking & Reports – Metropolis Healthcare

How to Book the Neuronal Migration Disorder Gene Panel and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Neuronal Migration Disorder Gene Panel, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced molecular diagnostic technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Neuronal Migration Disorder Gene Panel Available Near You?

Yes, Metropolis Healthcare offers home sample collection for the Neuronal Migration Disorder Gene Panel. This service reduces the need for travel and ensures professional sample handling while maintaining strict quality standards.

How Long Does It Take to Get a Neuronal Migration Disorder Gene Panel Report?

Reports are usually available after 4 weeks once the sample reaches the lab.
Note: Reporting time may vary based on your location.

Where Can I See or Get Neuronal Migration Disorder Gene Panel Results?

  1. Metropolis Healthcare website or mobile app
    You can access your test results through the Metropolis Healthcare website or mobile app using your login credentials.
  2. Email or WhatsApp
    Reports are also shared via email or WhatsApp.
  3. Physical copy from the lab
    You may collect a physical copy directly from the Metropolis Lab if required.

Interpreting Neuronal Migration Disorder Gene Panel Results

What Your Neuronal Migration Disorder Gene Panel Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
Neuronal migration disorder related genes No disease causing variant detected Neuronal migration disorder affecting brain development Symptoms may be due to other genetic or non genetic neurological conditions

Understanding Abnormal Neuronal Migration Disorder Gene Panel Results by Parameter

Gene Group What a Pathogenic Variant May Indicate
DCX, LIS1 related genes Lissencephaly or smooth brain disorders
TUBA and TUBB genes Tubulin related brain malformations
RELN, ARX, FLNA Cortical development and neuronal positioning defects
PI3K pathway genes Brain overgrowth and cortical malformations

How Should You Prepare for a Neuronal Migration Disorder Gene Panel?

This genetic test requires minimal preparation. Please keep the following in mind:

  • No fasting required: You can eat and drink normally before the test
  • Normal hydration: Maintain your usual fluid intake
  • Medication details: Inform your doctor about all medicines or supplements you take
  • Clinical history: Share details of developmental concerns and family history
  • Consent forms: Ensure the test requisition form and genetic history details are completed

How Is a Neuronal Migration Disorder Gene Panel Done? (Step-by-Step Procedure)

The test is performed using a simple blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible.
  • Cleaning: The puncture site is cleaned with antiseptic.
  • Sample Collection: A sterile needle is used to draw about 3 to 5 ml of blood into an EDTA vacutainer.
  • Completion: The needle is removed, and a bandage is applied.
  • Processing: The sample is analysed using Next Generation Sequencing to identify gene mutations linked to neuronal migration disorders.

Conditions That May Affect Neuronal Migration Disorder Gene Panel Accuracy

Certain patient related factors may influence test interpretation:

  • Recent blood transfusion may affect genetic analysis
  • Incomplete or incorrect clinical information can limit interpretation
  • Mosaic genetic changes may be difficult to detect
  • Variants of uncertain significance may require additional family studies

Diseases That a Neuronal Migration Disorder Gene Panel Can Help Detect

  • Lissencephaly
  • Polymicrogyria
  • Heterotopia
  • Other neuronal migration and cortical development disorders

References

  1. Barkovich A.J., Guerrini R., Kuzniecky R.I., Jackson G.D., Dobyns W.B. (2012). A developmental and genetic classification for malformations of cortical development. Neurology, 79(7), 709–718. PMID: 22855827
  2. Guerrini R., Dobyns W.B. (2014). Malformations of cortical development: Clinical features and genetic causes. Lancet Neurology, 13(7), 710–726. PMID: 24932993
  3. Romero D.M., Bahi Buisson N., Dobyns W.B. (2018). Brain malformations and developmental epileptic encephalopathies. Seminars in Neurology, 38(5), 544–556. PMID: 30380568
  4. Poirier K., Saillour Y., Bahi Buisson N., et al. (2013). Mutations in tubulin genes and neuronal migration disorders. Human Molecular Genetics, 22(3), 485–493. PMID: 23175433

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

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Precision
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  • Real-time tracking of phlebotomist arrival and report generation
  • Fully digital report delivery—view from mobile or desktop instantly
  • Continuous monitoring of turnaround times to ensure accuracy and speed
  • Dedicated support team to resolve any delays or queries quickly

Why Metropolis Healthcare?

Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

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