NextGen geneCore Somatic 161 gene panel
NextGen geneCore Somatic 161 gene panel** Price
Brief Details
What is a NextGen geneCore Somatic 161 Gene Panel?
The NextGen geneCore Somatic 161 Gene Panel is an advanced diagnostic test that uses Next-Generation Sequencing (NGS) technology to analyse the DNA of cancer cells. This comprehensive genomic test simultaneously examines 161 specific genes within a tumour's DNA to identify somatic mutations—genetic changes that occur during a person's lifetime and can drive cancer growth and spread.
The test helps create a detailed genetic map of your cancer, enabling your oncologist to develop a personalised treatment plan tailored to your tumour's unique characteristics.
What does the NextGen geneCore Somatic 161 Gene Panel measure?
This comprehensive genetic test provides crucial information about your cancer by measuring several important aspects:
- Somatic mutations - Genetic alterations that develop in cancer cells, including point mutations, insertions, and deletions.
- Actionable genetic targets - Specific mutations that can be treated with targeted therapies or immunotherapies.
- Treatment response biomarkers - Molecular indicators that predict how well a patient might respond to certain cancer treatments.
- Prognostic markers - Genetic changes that help doctors understand cancer behaviour and likely progression.
- Drug resistance patterns - Mutations that may indicate resistance to specific treatments.
- Therapy selection guidance - Information to help oncologists choose the most effective treatment approach.
NextGen geneCore Somatic 161 Gene Panel: Who Needs It and Why It's Done
Who should get a NextGen geneCore Somatic 161 Gene Panel?
This specialised genetic test is recommended for specific patient groups who can benefit from precision cancer care:
- Patients with confirmed solid tumours - Including lung cancer, breast cancer, colon cancer, pancreatic cancer, ovarian cancer, and prostate cancer.
- Individuals with advanced or metastatic cancer - When cancer has spread beyond its original location.
- Patients with recurrent cancer - When cancer returns after initial treatment.
- Candidates for targeted therapy - Those being considered for precision medicine approaches.
- Patients with treatment-resistant cancers - When standard treatments haven't been effective.
- Individuals eligible for clinical trials - To identify potential participation in experimental treatments.
Why is a NextGen geneCore Somatic 161 Gene Panel done?
This test enables precision oncology by providing a detailed genetic blueprint of the tumour, allowing doctors to select targeted therapies that are most likely to be effective while potentially reducing side effects compared to traditional treatments.
Importance of a NextGen geneCore Somatic 161 Gene Panel
The NextGen geneCore Somatic 161 Gene Panel represents a significant advancement in modern cancer care. This test shifts treatment from a generalised approach to highly personalised medicine, where therapy is tailored to your tumour's unique genetic characteristics.
The test's clinical importance lies in guiding precision treatment decisions. By identifying specific mutations driving your cancer, doctors can prescribe targeted drugs that attack those particular abnormalities, often with fewer side effects than traditional chemotherapy. This approach can lead to better treatment outcomes and improved survival rates for many patients.
Additionally, the test helps avoid ineffective treatments, saving valuable time and sparing you from unnecessary side effects. The genetic information can also help determine if you're eligible for clinical trials testing new, innovative cancer treatments.
NextGen geneCore Somatic 161 Gene Panel Booking & Reports – Metropolis Healthcare India
How to Book a NextGen geneCore Somatic 161 Gene Panel?
- Simple Online Booking
Booking can be done through the Metropolis Healthcare App or website. Select NextGen geneCore Somatic 161 Gene Panel, choose a convenient time slot, and visit the nearest Metropolis Lab.
- Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
- Accurate Laboratory Testing
Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results.
- Quick & Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is home sample collection for NextGen geneCore Somatic 161 Gene Panel available near you?
No, Metropolis Healthcare does not provide home sample collection for the NextGen geneCore Somatic 161 Gene Panel. The test requires a tissue sample from your tumour, which must be obtained through a biopsy procedure at a medical facility. Our NABL & CAP accredited laboratories process your sample using advanced next-generation sequencing technology, delivering accurate results.
How Long Does It Take to Get a NextGen geneCore Somatic 161 Gene Panel Report?
Reports are usually available after 4 weeks once the sample reaches the lab.
Note: Reporting time may vary depending on your location.
Where can I see or get NextGen geneCore Somatic 161 Gene Panel results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.
Interpreting NextGen geneCore Somatic 161 Gene Panel Results
What Your NextGen geneCore Somatic 161 Gene Panel Results May Indicate
The following table provides guidance on understanding your genetic test results for the key genes analysed in this comprehensive panel:
|
Parameter |
Result Type |
Clinical Significance |
|
Gene Mutations |
Detected/Not Detected |
One or more genetic alterations identified that may guide treatment decisions |
|
Actionable Variants |
Present |
Specific mutations that can be targeted with approved therapies |
|
Biomarkers |
Positive/Negative |
Indicators that predict response to targeted therapy or immunotherapy |
|
Tumour Mutation Burden |
High/Low |
Overall number of mutations that may influence immunotherapy effectiveness |
Conditions that May Affect NextGen geneCore Somatic 161 Gene Panel Accuracy
Several factors can influence your NextGen geneCore Somatic 161 Gene Panel results and should be discussed with your doctor:
- Tissue quality and age - Older or poorly preserved tissue samples may affect DNA quality and test accuracy.
- Tumour content in sample - Samples with low tumour cell percentage may not provide reliable results.
- Previous treatments - Chemotherapy or radiation therapy may alter the genetic profile of cancer cells.
- Sample contamination - Normal tissue mixed with tumour tissue can dilute the genetic signals.
- Technical factors - Laboratory processing conditions and sequencing depth can impact result quality.
- Clonal heterogeneity - Different parts of the same tumour may have different genetic profiles.
How is a NextGen geneCore Somatic 161 Gene Panel Done?
The NextGen geneCore Somatic 161 Gene Panel follows a sophisticated laboratory process to analyse your cancer's genetic profile:
- Sample preparation - The formalin-fixed paraffin-embedded tissue block is processed to extract high-quality DNA from cancer cells.
- DNA isolation - Advanced techniques separate cancer cell DNA from normal tissue DNA for accurate analysis.
- Library preparation - DNA is prepared and tagged for next-generation sequencing analysis.
- Sequencing process - All 161 genes are simultaneously analysed using cutting-edge sequencing technology.
- Data analysis - Sophisticated bioinformatics tools identify mutations, fusions, and other genetic alterations.
- Quality control - Multiple checkpoints ensure accurate and reliable results.
- Report generation - Results are compiled into a comprehensive report with treatment recommendations.
- Expert review - Molecular pathologists review findings before releasing the final report.
How Should You Prepare for a NextGen geneCore Somatic 161 Gene Panel?
Preparation for the NextGen geneCore Somatic 161 Gene Panel is straightforward since it uses existing tissue samples:
- No fasting required - You don't need to avoid food or drinks before the test.
- Gather clinical documents - Ensure your clinical history, histopathology report, and IHC (immunohistochemistry) report are available.
- Coordinate with your oncologist - Your doctor will arrange for the tissue sample to be sent to the laboratory.
- Discuss medications - Inform your healthcare team about all current medications, though they typically don't affect genetic testing results.
Diseases that a NextGen geneCore Somatic 161 Gene Panel Can Help Detect
This comprehensive genetic panel assists in the diagnosis, treatment planning, and management of various cancer types:
- Breast cancer - Identifies BRCA mutations and other actionable targets for personalised treatment.
- Lung cancer - Detects EGFR, ALK, and ROS1 alterations for targeted therapy selection.
- Colon cancer - Analyses KRAS, BRAF, and other mutations affecting treatment response.
- Pancreatic cancer - Identifies genetic alterations that may guide treatment decisions.
- Ovarian cancer - Detects homologous recombination deficiency and other therapeutic targets.
- Prostate cancer - Analyses genes affecting hormone therapy response and treatment selection.
- Bone marrow cancers - Identifies mutations relevant to haematological malignancies.
- Various solid tumours - Provides genetic insights for multiple types of cancer.
NextGen geneCore Somatic 161 Gene Panel/Packages that You Can Book With Metropolis Healthcare
Metropolis Healthcare offers several complementary genetic tests that work alongside the NextGen geneCore Somatic 161 Gene Panel for comprehensive cancer care:
|
Test/Package Name |
Purpose/Highlights |
|
Focuses specifically on BRCA1 and BRCA2 gene mutations in tumour tissue for targeted therapy guidance |
|
|
Analyses homologous recombination repair genes to identify patients who may benefit from PARP inhibitor therapy |
|
|
Measures the total number of mutations in tumour DNA to predict immunotherapy response |
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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.
In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.