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Krabbe disease (GALC) gene analysis
₹ 18500
Krabbe Disease (GALC) Gene Analysis Test
₹ 18500 ₹ 18500

Krabbe Disease (GALC) Gene Analysis Test

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Krabbe disease (GALC) gene analysis Price

₹ 18500

Brief Details

Preparation
No special preparation required
Also Known As
Krabbe disease (GALC) gene analysis
Fasting
Fasting not required
Reporting Time
After 4 weeks
Purpose
To detect genetic mutations in the GALC gene causing Krabbe disease

What is the Krabbe Disease (GALC) Gene Analysis Test?

The Krabbe Disease (GALC) Gene Analysis Test is a genetic blood test used to diagnose Krabbe disease, a rare inherited disorder that affects the nervous system. The condition leads to progressive damage of the brain and peripheral nerves due to the loss of protective myelin covering nerve cells.

This test analyses the GALC gene using next generation sequencing technology to identify disease causing genetic changes. Confirming a pathogenic variant helps establish the diagnosis, assess disease type, and support clinical decision making. The test requires a blood sample collected in an EDTA tube.

What Does the Krabbe Disease (GALC) Gene Analysis Test Measure?

This genetic test looks for disease causing changes in the GALC gene:

  • Detects pathogenic variants responsible for Krabbe disease
  • Helps confirm the cause of progressive neurodegeneration
  • Supports early diagnosis in infants and children with developmental regression
  • Aids genetic counselling and family screening
  • Guides prognosis and long-term care planning

Krabbe Disease (GALC) Gene Analysis Test: Who Needs It and Why It’s Done

What Symptoms May Call for a Krabbe Disease (GALC) Gene Analysis Test?

Doctors may recommend this test if an infant, child, or adult shows features suggestive of Krabbe disease, such as:

  • Developmental delay or loss of milestones
  • Muscle stiffness or weakness
  • Feeding difficulties and irritability in infants
  • Seizures or abnormal movements
  • Vision or hearing impairment

Who Should Get a Krabbe Disease (GALC) Gene Analysis Test?

This test may be advised for:

  • Infants with suspected inherited neurodegenerative disorders
  • Children or adults with unexplained leukodystrophy on brain imaging
  • Individuals with a family history of Krabbe disease
  • Couples planning a pregnancy with known carrier status
  • Families seeking genetic counselling and risk assessment

Why is the Krabbe Disease (GALC) Gene Analysis Test Done?

The test helps confirm the genetic cause of Krabbe disease, enabling accurate diagnosis, timely management, and informed counselling for affected families.

Krabbe Disease (GALC) Gene Analysis Test Booking & Reports – Metropolis Healthcare

How to Book the Krabbe Disease (GALC) Gene Analysis Test and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Krabbe Disease (GALC) Gene Analysis Test, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced molecular diagnostic technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Krabbe Disease (GALC) Gene Analysis Test Available Near You?

Yes, Metropolis Healthcare offers home sample collection for the Krabbe Disease (GALC) Gene Analysis Test. This service saves you time, reduces the need for travel, and ensures professional sample handling while maintaining strict quality standards.

In How Much Time Will I Get the Krabbe Disease (GALC) Gene Analysis Test Report?

Reports are usually available after 4 weeks once the sample reaches the lab.
Note: Reporting time may vary based on your location.

Where Can I See or Get Krabbe Disease (GALC) Gene Analysis Test Results?

You can access your test reports through the Metropolis Healthcare website or mobile app using your login credentials. Reports are also sent via email or WhatsApp, and you may collect a physical copy from the Metropolis Lab if required.

Interpreting Krabbe Disease (GALC) Gene Analysis Test Results

What Your Krabbe Disease (GALC) Gene Analysis Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
GALC gene No disease causing variant detected Confirmed genetic Krabbe disease or carrier status Symptoms may be due to other leukodystrophies or variants not detected by this analysis

Understanding Abnormal Krabbe Disease (GALC) Gene Analysis Results

Finding What It May Indicate
Pathogenic GALC variant Krabbe disease with progressive neurological involvement
No pathogenic variant Alternative neurological or metabolic disorder may need evaluation

How Should You Prepare for a Krabbe Disease (GALC) Gene Analysis Test?

This genetic test requires minimal preparation from your side:

  • No fasting required: You can eat and drink normally before sample collection
  • Normal hydration: Maintain your usual fluid intake
  • Medication disclosure: Inform your doctor about any medicines or supplements you are taking
  • Share clinical history: Provide relevant medical and family history as advised
  • Consent and documentation: Ensure the test requisition form and genetic history details are completed

How Is a Krabbe Disease (GALC) Gene Analysis Test Done? (Step-by-Step Procedure)

The test is performed using a standard blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible
  • Cleaning: The puncture site is cleaned with antiseptic
  • Sample Collection: A sterile needle is used to draw about 3 to 5 ml of blood into an EDTA vacutainer
  • Completion: The needle is removed, and a bandage is applied
  • Processing: The sample undergoes next generation sequencing to analyse the GALC gene

Conditions That May Affect Krabbe Disease (GALC) Gene Analysis Test Accuracy

Certain patient related factors may influence test interpretation:

  • Recent blood transfusion, which may affect genetic analysis
  • Incomplete or inaccurate family history details
  • Presence of rare or mosaic genetic changes requiring clinical correlation

Diseases That the Krabbe Disease (GALC) Gene Analysis Test Can Help Detect

  • Krabbe disease
  • GALC related leukodystrophies
  • Inherited neurodegenerative disorders

References

  1. Wenger D.A., Rafi M.A., Luzi P. (2000). Krabbe disease: genetic aspects and progress toward therapy. Molecular Genetics and Metabolism, 70(1), 1–9. PMID: 10924269
  2. Duffner P.K., Barczykowski A., Jalal K., et al. (2011). Early infantile Krabbe disease: results of the World Wide Registry. Pediatric Neurology, 45(3), 141–148. PMID: 21839433
  3. Escolar M.L., Poe M.D., Provenzale J.M., et al. (2005). Transplantation of umbilical cord blood in babies with infantile Krabbe’s disease. New England Journal of Medicine, 352(20), 2069–2081. PMID: 15901860

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

Regular exercise, a balanced diet, avoiding smoking, maintaining a healthy weight, and managing stress all help reduce heart disease risk.

Common signs include irritability, trouble sleeping, headaches, difficulty concentrating, and muscle tension.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

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  • Dedicated support team to resolve any delays or queries quickly

Why Metropolis Healthcare?

Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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About Us

Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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