Bilirubin Total Serum
Bilirubin Total, Serum Price
Bilirubin is a yellowish pigment that is made by breakdown of haemoglobin and myoglobin. Major production comes from break down of red blood cells. In blood this bilirubin is unconjugated (indirect) and cannot be excreted in urine or bile but can pass through placenta and into brain. In liver it is conjugated (direct) which can now be excreted in bile. A total bilirubin test measures both bilirubin components present in the blood.
Testing for bilirubin is conducted as a part of a group test. It is done to assess the conditions of the liver. The bilirubin pigment is created by the breakdown of red blood cells. The same is passed through the liver. It is then excreted from the body. Let us understand the pigment of bilirubin and the bilirubin total serum test.
What is Bilirubin?
Bilirubin is an orange-yellow pigment. It occurs in the human body. It normally occurs when there is a breakdown of haemoglobin and myoglobin in the body. Haemoglobin is the protein in the red blood cells. It transports oxygen to organs and tissues in your body. It carries carbon dioxide back to the lungs.
Myoglobin on the other hand is the protein. It is found mainly in muscle tissue. Here, myoglobin plays a role as an intracellular storage site for oxygen. However, the major production of bilirubin in you occurs from the disintegration of the red blood cells.
Primarily, the liver is responsible for taking bilirubin in its direct form. The liver then breaks down the bilirubin into bile for being excreted by the body. In the unconjugated or indirect form, bilirubin cannot be passed away from the human body as bile or urine. Rather it makes its way to the brain via your placenta.
A total bilirubin test measures the presence of both conjugated and unconjugated bilirubin in your blood.
Written by: Dr.Shibani R, Medical Writer, Medical Affairs
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