Next Gen Pulmocore 20 gene Panel
NextGen Pulmocore 20 Gene Panel by NGS, FFPE Tissue** Price
Brief Details
What is a PulmoCORE 20 Gene Panel?
The PulmoCORE 20 Gene Panel is a specialised genetic test that examines 20 specific genes in tissue samples using next-generation sequencing (NGS) technology. This advanced molecular test analyses your DNA to identify genetic changes that may influence lung cancer development and treatment response.
The test helps detect inherited genetic mutations and acquired changes that can significantly increase your risk of developing certain lung diseases, particularly non-small cell lung cancer (NSCLC) and other pulmonary conditions.
What does the PulmoCORE 20 Gene Panel measure?
This comprehensive genetic test serves several important purposes in lung cancer diagnosis and management:
- Identifies genetic mutations - Detects specific changes in genes that drive cancer growth and development.
- Guides targeted therapy selection - Helps doctors choose the most effective treatments based on your genetic profile.
- Determines treatment eligibility - Identifies patients who may benefit from specific FDA-approved targeted therapies.
- Assesses prognosis - Provides information about likely disease progression and outcomes.
- Supports clinical trial participation - Identifies genetic markers that may qualify you for experimental treatments.
- Enables personalised medicine - Tailors treatment approaches based on your unique genetic makeup.
- Family health information: Provides valuable genetic information that may be relevant for your relatives.
PulmoCORE 20 Gene Panel: Who Needs It and Why It's Done
Who should get a PulmoCORE 20 Gene Panel?
This specialised genetic test is typically recommended for specific patient groups:
- Individuals diagnosed with non-small cell lung cancer requiring treatment planning.
- Patients with a strong family history of lung cancer or pulmonary diseases.
- People diagnosed with lung cancer at a younger age than typically expected.
- Individuals who have had multiple types of cancer, including lung cancer.
- Patients whose tumours show specific characteristics that suggest genetic involvement.
- Those whose family members have tested positive for lung cancer-related genetic mutations.
Why is a PulmoCORE 20 Gene Panel done?
This test is performed to identify genetic factors that influence lung cancer development and guide personalised treatment decisions. It helps doctors select the most effective targeted therapies and provides valuable information for family health planning.
Importance of a PulmoCORE 20 Gene Panel
The PulmoCORE 20 Gene Panel plays a crucial role in modern lung cancer care by enabling precision medicine approaches. By identifying specific genetic alterations in your tumour tissue, doctors can select targeted therapies that work specifically against your cancer's genetic weaknesses. This targeted approach often leads to better treatment outcomes and fewer side effects compared to traditional chemotherapy.
The test also provides crucial information for ongoing health monitoring and helps identify family members who may benefit from genetic counselling or increased surveillance. Understanding your genetic risk empowers you and your family to make informed healthcare decisions.
PulmoCORE 20 Gene Panel Booking & Reports – Metropolis Healthcare India
How to Book a PulmoCORE 20 Gene Panel?
- Simple Online Booking
Booking can be done through the Metropolis Healthcare App or website. Select the PulmoCORE 20 Gene Panel, choose a convenient time slot, and visit the nearest Metropolis Lab.
- Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
- Accurate Laboratory Testing
Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results.
- Quick & Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is home sample collection for PulmoCORE 20 Gene Panel available near you?
No, Metropolis Healthcare does not provide home sample collection for the PulmoCORE 20 Gene Panel. This test is performed on tissue blocks obtained during biopsy or surgery procedures at healthcare facilities. Our expert pathologists and advanced NGS technology deliver accurate, reliable results that help guide your treatment decisions with confidence and precision.
How Long Does It Take to Get a PulmoCORE 20 Gene Panel Report?
Reports are usually available after 20 days by 6:00 PM once the sample reaches the lab.
Note: Reporting time may vary depending on your location.
Where can I see or get PulmoCORE 20 Gene Panel results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.
Interpreting PulmoCORE 20 Gene Panel Results
What Your PulmoCORE 20 Gene Panel Results May Indicate
Your PulmoCORE 20 Gene Panel results provide detailed genetic information about your lung cancer. The following table explains what different findings might mean:
|
Parameter |
Result Type |
Clinical Interpretation |
|
Hotspot Mutations |
Mutation Detected/Not Detected |
Specific genetic changes that may respond to targeted therapies |
|
Gene Fusions |
Fusion Present/Absent |
Abnormal gene connections that may be treatable with specific drugs |
|
Copy Number Variations |
Amplification/Deletion/Normal |
Changes in gene copies that affect cancer behaviour and treatment options |
|
Variant Classification |
Tier 1-4 (AMP) or Pathogenic/Benign (ACMG) |
Clinical significance of detected genetic changes for treatment decisions |
Conditions that May Affect PulmoCORE 20 Gene Panel Accuracy
Several factors can influence the accuracy and interpretation of your genetic test results:
- Tissue quality and preservation - Poorly preserved or degraded tissue samples may affect sequencing quality.
- Tumour cell percentage - Samples with insufficient cancer cells may not provide reliable results.
- Sample contamination - Normal tissue mixed with cancer tissue can dilute genetic signals.
- Technical limitations - Some genetic changes may be below the detection threshold of the test.
- Genetic heterogeneity - Different parts of the tumour may have different genetic profiles.
- Previous treatments - Chemotherapy or radiation may alter the genetic landscape of cancer cells.
How is a PulmoCORE 20 Gene Panel Done?
The genetic testing process involves several carefully controlled steps to ensure accurate results:
- Tissue sample preparation - Your formalin-fixed, paraffin-embedded tissue block is processed in the pathology lab.
- DNA and RNA extraction - Genetic material is carefully extracted from cancer cells in the tissue.
- Quality assessment - The extracted genetic material undergoes quality checks to ensure suitability for testing.
- Library preparation - Your genetic material is prepared using specialised AmpliSeq technology for sequencing.
- Next-generation sequencing - Advanced Ion S5 System analyses your genetic code for mutations and alterations.
- Data analysis - Sophisticated software compares your results against reference databases.
- Expert interpretation - Qualified molecular pathologists review and interpret your genetic findings.
- Report generation - Your personalised results are compiled into a comprehensive clinical report.
How Should You Prepare for a PulmoCORE 20 Gene Panel?
Preparing for your PulmoCORE 20 Gene Panel is straightforward:
- No fasting required - You can eat and drink normally before sample collection.
- Provide clinical history - Complete medical history is mandatory for accurate interpretation.
- Continue regular medications - No need to stop current treatments unless advised by your doctor.
- Inform about supplements - Tell your healthcare provider about all medications and supplements you take.
Diseases that a PulmoCORE 20 Gene Panel Can Help Detect
This comprehensive genetic test can help identify several lung-related conditions:
- Non-Small Cell Lung Cancer (NSCLC) - The most common type of lung cancer.
- Pulmonary adenocarcinoma - A subtype of NSCLC affecting lung tissue.
PulmoCORE 20 Gene Panel/Packages that You Can Book With Metropolis Healthcare
Metropolis Healthcare offers several related tests to provide comprehensive lung health risk assessment and cancer screening:
|
Test/Package Name |
Purpose/Highlights |
|
Comprehensive screening for lung cancer markers |
|
|
Detects tuberculosis and other respiratory infections |
|
|
Specific genetic marker testing for targeted therapy |
Frequently asked questions
Find quick answers to the most common questions about health tests, bookings, and reports.
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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.
In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.