Endomysial Antibody IgG antibody Serum
Endomysial - IgG antibody, Serum Price
Circulating IgG endomysial antibodies are present in 70% to 80% of patients with dermatitis herpetiformis or celiac disease, and in nearly all such patients who have high grade gluten-sensitive enteropathy and are not adhering to a gluten-free diet
Endomysial Antibody IgG (IgG-EMA) is a type of autoantibody found in the blood serum of individuals with certain autoimmune disorders, such as celiac disease.
The endomysium is a thin layer of connective tissue that surrounds individual muscle fibers, and IgG-EMA is an antibody that targets this tissue. In celiac disease, the immune system mistakenly identifies gluten, a protein found in wheat, barley, and rye, as a foreign invader and produces IgG-EMA antibodies that attack the endomysium in the small intestine. This can lead to inflammation and damage to the intestinal lining, which can cause a range of symptoms including diarrhoea, abdominal pain, and malabsorption of nutrients.
The detection of IgG-EMA in serum is commonly used as a diagnostic tool for celiac disease, In patients with low levels of IgA and children less than 3 years of age
Associated Tests:
E0027 Endomysial Antibody IgA antibody Serum
C0285 Coeliac disease profile-2 Comprehensive
C0079 Celiac Disease Profile
C0284 Coeliac Disease Profile-1
Written by: Supriya Kulkarni, Lead-Content & Training
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