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Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel
₹ 19400
Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel
₹ 19400 ₹ 19400

Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Price

₹ 19400

Brief Details

Preparation
No special preparation required
Also Known As
Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel by NGS
Fasting
Fasting not required
Reporting Time
Around 4 weeks
Purpose
To identify genetic mutations causing Leigh syndrome and mitochondrial encephalopathy

What Is the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel?

The Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel is a genetic blood test used to diagnose severe neurological disorders caused by mitochondrial dysfunction. These conditions affect how cells produce energy, particularly impacting the brain, muscles, and nervous system.

This test analyses a group of genes known to be associated with Leigh syndrome and related mitochondrial encephalopathies. It helps your doctor confirm a genetic diagnosis when clinical symptoms and imaging findings suggest a mitochondrial disorder.

What Does the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Measure?

This test examines genes involved in mitochondrial energy production and neurological function:

  • Detection of pathogenic genetic variants linked to Leigh syndrome
  • Identification of mitochondrial encephalopathies with overlapping symptoms
  • Differentiation from other metabolic or neurological conditions
  • Support for prognosis assessment and long term care planning

Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel: Who Needs It and Why It’s Done

What Symptoms May Call for a Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel?

Your doctor may suggest this test if you or your child experiences:

  • Developmental delay or regression
  • Poor muscle tone or muscle weakness
  • Recurrent vomiting or feeding difficulties
  • Seizures or movement disorders
  • Abnormal brain MRI findings such as leukoencephalopathy
  • Unexplained neurological decline

Who Should Get a Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel?

This test is recommended for:

  • Infants and children with suspected mitochondrial disorders
  • Adults with progressive neurological symptoms of unclear cause
  • Patients with MRI findings suggestive of mitochondrial encephalopathy
  • Individuals with a family history of mitochondrial disease
  • Families seeking genetic counselling and risk assessment

Why Is the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Done?

The test helps confirm a genetic cause for neurological symptoms, enabling accurate diagnosis, appropriate supportive care, and informed family counselling.

Importance of the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel

A confirmed genetic diagnosis helps avoid repeated testing and supports early intervention. Understanding the underlying cause allows your care team to guide symptom management, nutritional support, and long term planning, while also providing families with clarity about inheritance patterns and future risks.

Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Booking & Reports – Metropolis Healthcare

How to Book the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced next generation sequencing technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Available Near You?

Yes, Metropolis Healthcare offers home sample collection for the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel. This service ensures professional sample handling, reduces travel, and maintains strict quality standards throughout the testing process.

In How Much Time Will I Get the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Report?

Reports are usually available in around 4 weeks once the sample reaches the lab.
Note: Reporting time may vary based on your location.

Where Can I See or Get Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Results?

You can view and download your reports through the Metropolis Healthcare website or app. Reports are also sent via email or WhatsApp, and you may collect a physical copy from the Metropolis Lab if required.

Interpreting Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Results

What Your Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
Leigh syndrome and mitochondrial genes No pathogenic variant detected Genetic confirmation of Leigh syndrome or mitochondrial encephalopathy Symptoms may be due to non-genetic, acquired, or currently undetectable causes

Understanding Abnormal Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Results by Condition Group

Gene or Condition Group What a Pathogenic Variant May Indicate
Mitochondrial respiratory chain genes Leigh syndrome
Nuclear mitochondrial genes Mitochondrial encephalopathy
Energy metabolism genes Neurodegenerative metabolic disorders

How Should You Prepare for a Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel?

This test requires minimal preparation from your side:

  • No fasting required: You can eat and drink normally
  • Continue medications: Do not stop prescribed medicines unless advised by your doctor
  • Inform your doctor: Share details of symptoms, MRI findings, and family history
  • Complete forms: Ensure the test requisition form and genetic history details are provided
  • Normal hydration: Drink water as you usually would before sample collection

How Is a Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Done? (Step-by-Step Procedure)

The test is performed using a standard blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible
  • Cleaning: The puncture site is cleaned with an antiseptic
  • Sample Collection: About 3 to 5 ml of blood is drawn into an EDTA vacutainer using a sterile needle
  • Completion: The needle is removed, and a bandage is applied
  • Processing: The sample is analysed using next generation sequencing to identify genetic variants

Conditions That May Affect Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Accuracy

Certain patient-related factors may influence result interpretation:

  • Incomplete clinical or family history information
  • Mosaic genetic variants present at low levels
  • Advanced disease stage affecting clinical correlation
  • Genetic variants outside the tested gene panel

Diseases That the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Can Help Detect

  • Leigh syndrome
  • Mitochondrial encephalopathy
  • Mitochondrial neurogastrointestinal encephalomyopathy
  • Inherited metabolic neurodegenerative disorders

References

  1. Rahman S., Blok R.B., Dahl H.H.M., et al. (1996). Leigh syndrome: Clinical features and biochemical and DNA abnormalities. Annals of Neurology, 39(3), 343–351. PMID: 8602753
  2. Lake N.J., Compton A.G., Rahman S., Thorburn D.R. (2016). Leigh syndrome: One disorder, more than 75 monogenic causes. Annals of Neurology, 79(2), 190–203. PMID: 26694003
  3. Finsterer J. (2008). Leigh and Leigh-like syndrome in children and adults. Pediatric Neurology, 39(4), 223–235. PMID: 18805344

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Choose precision On time, every time!

Precision
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  • Real-time tracking of phlebotomist arrival and report generation
  • Fully digital report delivery—view from mobile or desktop instantly
  • Continuous monitoring of turnaround times to ensure accuracy and speed
  • Dedicated support team to resolve any delays or queries quickly

Why Metropolis Healthcare?

Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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