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Kallmann syndrome gene panel
₹ 19400
Kallmann Syndrome Gene Panel
₹ 19400 ₹ 19400

Kallmann Syndrome Gene Panel

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Kallmann syndrome gene panel Price

₹ 19400

Brief Details

Preparation
No special preparation required
Also Known As
Kallmann Syndrome Gene Panel by NGS
Fasting
Fasting not required
Reporting Time
After 4 weeks
Purpose
To detect genetic mutations causing Kallmann syndrome and support diagnosis, treatment planning, and family risk assessment

What is the Kallmann Syndrome Gene Panel?

The Kallmann Syndrome Gene Panel is a genetic blood test used to diagnose Kallmann syndrome, a rare inherited condition that affects sexual development and the sense of smell. It is a form of hypogonadotropic hypogonadism, where the body does not produce enough hormones needed for puberty and reproductive function.

This test analyses specific genes involved in hormone regulation and olfactory development using Next Generation Sequencing technology. It requires an EDTA blood sample and helps doctors confirm the diagnosis, plan hormone therapy, and assess genetic risk for family members.

What Does the Kallmann Syndrome Gene Panel Measure?

This genetic test looks for changes in genes responsible for hormonal signalling and reproductive development:

  • Detection of disease causing variants linked to Kallmann syndrome
  • Differentiation of Kallmann syndrome from other endocrine or pubertal disorders
  • Identification of inherited causes of delayed or absent puberty
  • Support for hormone replacement and fertility planning
  • Guidance for genetic counselling, family screening, and prenatal evaluation

Kallmann Syndrome Gene Panel: Who Needs It and Why It’s Done

What Symptoms May Call for a Kallmann Syndrome Gene Panel?

Doctors may recommend this test if you or your child experience symptoms such as:

  • Delayed or absent puberty
  • Reduced or absent sense of smell
  • Incomplete development of secondary sexual characteristics
  • Infertility or low sex hormone levels
  • Small testes in males or absent menstrual periods in females

Who Should Get a Kallmann Syndrome Gene Panel?

  • Adolescents with delayed puberty and hormonal abnormalities
  • Adults with infertility linked to low gonadotropin levels
  • Individuals with loss of smell and reproductive hormone deficiency
  • Patients with a family history of Kallmann syndrome
  • Couples planning a pregnancy with known genetic risk

Why is a Kallmann Syndrome Gene Panel Done?

The test helps identify the genetic cause of Kallmann syndrome, allowing early treatment, appropriate hormone therapy, and informed reproductive and family planning decisions.

Importance of the Kallmann Syndrome Gene Panel

Early diagnosis of Kallmann syndrome is important because timely hormone replacement can support normal pubertal development, bone health, and fertility outcomes. This gene panel enables precise identification of the underlying genetic cause, helping your doctor personalise treatment plans and provide accurate counselling about long term health and reproductive options.

Kallmann Syndrome Gene Panel Booking & Reports – Metropolis Healthcare

How to Book the Kallmann Syndrome Gene Panel and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Kallmann Syndrome Gene Panel, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced molecular diagnostic technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Kallmann Syndrome Gene Panel Available Near You?

Yes, Metropolis Healthcare offers home sample collection for the Kallmann Syndrome Gene Panel. This service saves you time, reduces the need for travel, and ensures professional sample handling while maintaining strict quality standards.

How Long Does It Take to Get a Kallmann Syndrome Gene Panel Report?

Reports are usually available after 4 weeks once the sample reaches the lab.
Note: Reporting time may vary based on your location.

Where Can I See or Get Kallmann Syndrome Gene Panel Results?

  1. Metropolis Healthcare website or mobile app
    You can access your test results through the Metropolis Healthcare website or mobile app using your login credentials.
  2. Email or WhatsApp
    Reports are also shared via email or WhatsApp.
  3. Physical copy from the lab
    You may collect a physical copy directly from the Metropolis Lab if required.

Interpreting Kallmann Syndrome Gene Panel Results

What Your Kallmann Syndrome Gene Panel Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
Kallmann syndrome related genes No disease causing variant detected Kallmann syndrome causing hypogonadotropic hypogonadism Symptoms may be due to other endocrine or genetic conditions

Understanding Abnormal Kallmann Syndrome Gene Panel Test Results

Gene Group What a Pathogenic Variant May Indicate
KAL1 Impaired migration of hormone producing neurons and olfactory development
FGFR1 Defects in gonadotropin releasing hormone signalling
PROK2 and PROKR2 Abnormal development of olfactory bulbs and reproductive hormone pathways

How Should You Prepare for a Kallmann Syndrome Gene Panel?

This genetic test requires minimal preparation. Please keep the following points in mind:

  • No fasting required: You can eat and drink normally unless advised otherwise by your doctor
  • Normal hydration: Continue your usual fluid intake
  • Medication information: Inform your doctor about all medicines or supplements you are taking
  • Clinical history: Share relevant medical and family history to support accurate interpretation
  • Consent and forms: Ensure the test requisition form and genetic history details are completed

How Is a Kallmann Syndrome Gene Panel Done? (Step-by-Step Procedure)

The test is performed using a simple blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible.
  • Cleaning: The puncture site is cleaned with antiseptic.
  • Sample Collection: A sterile needle is used to draw about 3 to 5 ml of blood into an EDTA vacutainer.
  • Completion: The needle is removed, and a bandage is applied.
  • Processing: The sample is analysed using Next Generation Sequencing to identify gene mutations linked to Kallmann syndrome.

Conditions That May Affect Kallmann Syndrome Gene Panel Accuracy

Certain patient related factors may influence test interpretation:

  • Recent blood transfusion may affect genetic analysis
  • Incomplete or incorrect clinical history can limit interpretation
  • Mosaic genetic changes may be harder to detect in some individuals
  • Variants of uncertain significance may require further family testing

Diseases That a Kallmann Syndrome Gene Panel Can Help Detect

  • Kallmann syndrome
  • Congenital hypogonadotropic hypogonadism
  • Genetic disorders of pubertal development

References

  1. Bianco S.D., Kaiser U.B. (2009). The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism. Nature Reviews Endocrinology, 5(10), 569–576. PMID: 19786987
  2. Dodé C., Hardelin J.P. (2009). Kallmann syndrome. European Journal of Human Genetics, 17(2), 139–146. PMID: 18985070
  3. Boehm U., Bouloux P.M., Dattani M.T., et al. (2015). Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism. Nature Reviews Endocrinology, 11(9), 547–564. PMID: 26206184

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

Regular exercise, a balanced diet, avoiding smoking, maintaining a healthy weight, and managing stress all help reduce heart disease risk.

Common signs include irritability, trouble sleeping, headaches, difficulty concentrating, and muscle tension.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

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Precision
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  • Real-time tracking of phlebotomist arrival and report generation
  • Fully digital report delivery—view from mobile or desktop instantly
  • Continuous monitoring of turnaround times to ensure accuracy and speed
  • Dedicated support team to resolve any delays or queries quickly

Why Metropolis Healthcare?

Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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