NextGen Liquicore 118 gene Panel ( MSI)
NextGen Liquicore 118 gene Panel ( MSI)** Price
Brief Details
What is a NextGen Liquicore 118 Gene Panel (MSI)?
The NextGen Liquicore 118 gene Panel (MSI) is an advanced liquid biopsy test that uses Next-Generation Sequencing (NGS) technology to analyse cancer genetics from a simple blood sample. This ultra-sensitive test detects trace amounts of circulating tumour DNA (ctDNA) in your blood and evaluates genetic changes across 118 cancer-related genes.
The test helps doctors understand the unique genetic profile of your cancer and determine the best treatment approach, particularly for guiding immunotherapy decisions.
What Does the NextGen Liquicore 118 Gene Panel (MSI) Measure?
This comprehensive test measures several key aspects of your cancer's genetic makeup:
- Genomic alterations - Identifies mutations in 118 cancer-related genes that may be driving tumour growth.
- Circulating tumour DNA (ctDNA) - Detects DNA fragments released by cancer cells into your bloodstream.
- Microsatellite instability (MSI) - Evaluates 434 MSI markers to determine if cancer cells have faulty DNA repair systems.
- Homologous recombination repair (HRR) genes - Analyses 15 HRR genes involved in DNA repair mechanisms.
- Treatment response markers - Identifies genetic patterns that predict response to targeted therapies and immunotherapy.
NextGen Liquicore 118 gene Panel (MSI): Who Needs It and Why It's Done
What Symptoms May Call for a NextGen Liquicore 118 gene Panel (MSI)?
This test is typically ordered for patients already diagnosed with cancer rather than for initial symptom evaluation. However, the underlying cancer symptoms that may have led to diagnosis include:
- Unexplained weight loss and persistent fatigue
- Persistent pain or discomfort in specific body areas
- Changes in bowel or bladder habits
- Unusual lumps or masses in the body
- Persistent cough or breathing difficulties
- Changes in skin moles or unusual bleeding
Who should get a NextGen Liquicore 118 gene Panel (MSI)?
This specialised test is recommended for specific groups of cancer patients:
- Patients with advanced solid tumours - Particularly those with metastatic colorectal, endometrial, gastric cancers, breast cancer, or ovarian cancer.
- Patients where tissue biopsy is challenging - When surgical biopsy poses health risks or is not feasible.
- Patients considering immunotherapy - To determine MSI status and treatment suitability.
- Patients with treatment-resistant cancer - When current therapies are no longer effective.
- Patients needing personalised treatment plans - To identify targeted therapy options based on genetic profile.
Why is a NextGen Liquicore 118 gene Panel (MSI) done?
The test enables precision medicine by providing a comprehensive genetic profile of your cancer, allowing doctors to select the most effective personalised treatments and avoid therapies unlikely to work.
Importance of a NextGen Liquicore 118 gene Panel (MSI)
This advanced genetic test plays a crucial role in modern cancer care by enabling truly personalised treatment approaches. The test's ability to detect MSI status helps doctors identify patients who may respond exceptionally well to immunotherapy, potentially transforming treatment outcomes for various types of cancer including colorectal and gastric cancers.
By analysing 118 cancer-related genes, the test provides ongoing monitoring capabilities that traditional tissue biopsies cannot offer. This allows your medical team to track how your cancer responds to treatment and detect emerging resistance patterns, enabling timely adjustments to your care plan. The non-invasive nature of this liquid biopsy makes it particularly valuable for patients with kidney disorders or other health conditions that make surgical procedures risky.
NextGen Liquicore 118 gene Panel (MSI) Booking & Reports – Metropolis Healthcare India
How to Book a NextGen Liquicore 118 gene Panel (MSI)?
- Simple Online Booking
Booking can be done through the Metropolis Healthcare App or website. Select the NextGen Liquicore 118 Gene Panel (MSI), choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab.
- Safe Home Sample Collection
Our trained phlebotomists ensure the timely collection of your sample while strictly following all safety and hygiene protocols.
- Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
- Accurate Laboratory Testing
Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results.
- Quick & Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is home sample collection for NextGen Liquicore 118 gene Panel (MSI) available near you?
Yes, Metropolis Healthcare provides home blood sample collection for the NextGen Liquicore 118 Gene Panel (MSI). Our trained phlebotomists come to your doorstep with proper safety protocols and specialised collection tubes required for this advanced genetic test. This convenient service ensures you receive the same accurate results from our NABL & CAP accredited pathology lab without the stress of travelling to a facility.
How long does it take to get a NextGen Liquicore 118 gene panel (MSI) report?
Reports are usually available after 4 weeks by 6:00 PM once the sample reaches the lab.
Note: Reporting time may vary depending on your location.
Where can I see or get NextGen Liquicore 118 gene Panel (MSI) results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.
Interpreting NextGen Liquicore 118 gene Panel (MSI) Results
What Your NextGen Liquicore 118 Gene Panel (MSI) Results May Indicate
Your test results provide detailed genetic information about your cancer rather than traditional numerical values. The following table explains the key components of your report:
|
Parameters |
Result Type |
Clinical Significance |
|
Genomic Alterations |
Detected/Not Detected |
Identifies specific mutations that may guide targeted therapy selection |
|
MSI Status |
MSI-High (MSI-H) or MSS (Microsatellite Stable) |
MSI-H indicates potential good response to immunotherapy |
|
Circulating Tumour DNA |
Present/Absent with genetic profile |
Provides real-time information about cancer genetics and treatment response |
|
HRR Gene Mutations |
Pathogenic/Likely Pathogenic/Variant of Unknown Significance |
Indicates potential response to PARP inhibitors and other targeted treatments |
Conditions that May Affect NextGen Liquicore 118 gene Panel (MSI) Accuracy
Several factors can influence your NextGen Liquicore 118 gene panel results and should be discussed with your doctor:
- Recent cancer treatments, particularly chemotherapy or targeted therapy, may affect circulating tumour DNA levels in your blood.
- Blood transfusions received within the past few weeks may dilute circulating tumour DNA.
- Severe dehydration can concentrate blood components, potentially affecting sample quality.
- Certain medications may interfere with DNA analysis, though this is rare.
- Sample collection timing relative to treatment cycles may impact ctDNA detection.
- Haemolysed, lipemic, or clotted blood samples can affect test accuracy and may require recollection.
How is a NextGen Liquicore 118 gene Panel (MSI) Done?
The NextGen Liquicore 118 gene panel follows a systematic process to ensure accurate genetic analysis:
- A trained phlebotomist cleans the area on your arm with antiseptic solution.
- An elastic band is tied around your upper arm to make veins more visible.
- A small needle is inserted into a vein, and 9.5 ml of blood is collected into a specialised cell-free tube.
- The sample is immediately processed and stored at appropriate temperature conditions.
- Your blood is transported to our NABL & CAP accredited molecular pathology laboratory.
- Advanced next-generation sequencing technology analyses the DNA fragments.
- Expert pathologists interpret the complex genetic data to generate your comprehensive report.
How Should You Prepare for a NextGen Liquicore 118 gene Panel (MSI)?
Preparing for your NextGen Liquicore 118 gene Panel is straightforward and requires minimal preparation:
- No fasting required - You can eat and drink normally before the test.
- Continue regular medications - Take your prescribed medications as usual unless your doctor advises otherwise.
- Inform your doctor - Share your complete medical history, including current cancer treatments and medications.
- Bring required documents - Ensure you have your clinical history, histopathology, and immunohistochemistry (IHC) reports.
- Stay hydrated - Drink adequate water to ensure easy blood collection.
- Wear comfortable clothing - Choose clothing that allows easy access to your arm for blood collection.
Diseases that a NextGen Liquicore 118 gene Panel (MSI) Can Help Detect
The NextGen Liquicore 118 gene panel provides valuable genetic information for various types of cancer:
- Colorectal cancer - Identifies MSI status and actionable genetic mutations for treatment planning.
- Endometrial cancer - Detects genetic alterations that guide therapy selection and immunotherapy eligibility.
- Gastric cancers - Provides genetic profiling for personalised treatment approaches.
- Breast cancer - Identifies BRCA and other relevant genetic mutations for targeted therapy decisions.
- Ovarian cancer - Detects homologous recombination repair deficiencies and treatment-relevant genetic changes.
- Lynch syndrome-associated cancers - Identifies MSI patterns associated with hereditary cancer syndromes.
- Various solid tumours - Provides genetic insights for multiple cancer types to guide precision medicine approaches.
NextGen Liquicore 118 Gene Panel/Packages that You Can Book With Metropolis Healthcare
Metropolis Healthcare offers comprehensive genetic testing options to support your cancer care journey:
|
Test/Package Name |
Purpose/Highlights |
|
Focused MSI testing for Lynch syndrome and hereditary cancer detection |
|
|
Comprehensive panel of tumour markers for cancer screening and monitoring |
|
|
Genetic screening for chromosomal abnormalities during pregnancy |
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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.
In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.