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Hereditary Hyperoxaluria Gene Panel
₹ 19400
Hereditary Hyperoxaluria Gene Panel
₹ 19400 ₹ 19400

Hereditary Hyperoxaluria Gene Panel

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Hereditary Hyperoxaluria Gene Panel Price

₹ 19400

Brief Details

Preparation
No special preparation required
Also Known As
Primary Hyperoxaluria Gene Panel by NGS
Fasting
Fasting not required
Reporting Time
Around 4 weeks
Purpose
To detect genetic mutations causing primary hyperoxaluria and related kidney disorders

What Is the Hereditary Hyperoxaluria Gene Panel?

The Hereditary Hyperoxaluria Gene Panel is a genetic blood test used to diagnose primary hyperoxaluria, a rare inherited condition that leads to excess oxalate production in the body. High oxalate levels can cause recurrent kidney stones, kidney damage, and in severe cases, kidney failure.

This test analyses specific genes known to cause primary hyperoxaluria. It helps your doctor confirm a genetic diagnosis and distinguish this condition from other causes of kidney stones or renal disease.

What Does the Hereditary Hyperoxaluria Gene Panel Measure?

This test examines genes involved in oxalate metabolism:

  • Detection of pathogenic gene variants linked to primary hyperoxaluria
  • Identification of the specific type of primary hyperoxaluria
  • Differentiation from non-genetic causes of kidney stones
  • Assessment of inherited risk within families

Hereditary Hyperoxaluria Gene Panel: Who Needs It and Why It’s Done

What Symptoms May Call for a Hereditary Hyperoxaluria Gene Panel?

Your doctor may recommend this test if you have symptoms suggestive of a metabolic kidney disorder, such as:

  • Recurrent kidney stones, especially from a young age
  • Unexplained kidney damage or declining kidney function
  • Calcium oxalate stones that keep returning
  • Kidney stones in childhood or adolescence
  • Family history of kidney stones or kidney failure

Who Should Get a Hereditary Hyperoxaluria Gene Panel?

This test is advised for:

  • Individuals with early onset or recurrent kidney stones
  • Children or adults with unexplained kidney disease
  • Patients with suspected primary hyperoxaluria based on clinical findings
  • Families with a known history of primary hyperoxaluria
  • Individuals undergoing genetic counselling for inherited kidney disorders

Why Is a Hereditary Hyperoxaluria Gene Panel Done?

The test confirms whether kidney stone disease or kidney failure has a genetic cause, allowing your doctor to plan targeted treatment and long-term management.

Importance of the Hereditary Hyperoxaluria Gene Panel

Primary hyperoxaluria often worsens over time if not diagnosed early. Genetic testing allows prompt diagnosis, early treatment, and prevention of complications such as chronic kidney disease. Knowing the genetic cause also helps guide family screening, genetic counselling, and future care planning.

Hereditary Hyperoxaluria Gene Panel Booking & Reports – Metropolis Healthcare

How to Book the Hereditary Hyperoxaluria Gene Panel and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Hereditary Hyperoxaluria Gene Panel, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced next generation sequencing technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Hereditary Hyperoxaluria Gene Panel Available Near You?

Yes, Metropolis Healthcare offers home sample collection for the Hereditary Hyperoxaluria Gene Panel. This service reduces the need for hospital visits and ensures professional sample handling while maintaining strict quality standards.

In How Much Time Will I Get the Hereditary Hyperoxaluria Gene Panel Report?

Reports are usually available in around 4 weeks once the sample reaches the lab.
Note: Reporting time may vary based on your location.

Where Can I See or Get Hereditary Hyperoxaluria Gene Panel Results?

You can view and download your test reports through the Metropolis Healthcare website or app. Reports are also sent via email or WhatsApp, and you may collect a physical copy from the Metropolis Lab if required.

Interpreting Hereditary Hyperoxaluria Gene Panel Results

What Your Hereditary Hyperoxaluria Gene Panel Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
AGXT, GRHPR, HOGA1 No pathogenic variant detected Genetic diagnosis of primary hyperoxaluria Symptoms may be due to non-genetic or untested causes

Understanding Abnormal Hereditary Hyperoxaluria Gene Panel Results by Gene

Gene What a Pathogenic Variant May Indicate
AGXT Primary hyperoxaluria type 1
GRHPR Primary hyperoxaluria type 2
HOGA1 Primary hyperoxaluria type 3

How Should You Prepare for a Hereditary Hyperoxaluria Gene Panel?

This test requires minimal preparation from your side:

  • No fasting required: You can eat and drink normally
  • Continue medications: Do not stop any medicines unless advised by your doctor
  • Inform your doctor: Share details of kidney stone history and family history
  • Complete forms: Ensure the test requisition form and genetic history are provided
  • Normal hydration: Drink water as you usually would before sample collection

How Is a Hereditary Hyperoxaluria Gene Panel Done? (Step-by-Step Procedure)

The test is performed using a simple blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible
  • Cleaning: The puncture site is cleaned with an antiseptic
  • Sample Collection: About 3 to 5 ml of blood is drawn into an EDTA vacutainer using a sterile needle
  • Completion: The needle is removed, and a bandage is applied
  • Processing: The sample is analysed using next generation sequencing to detect genetic variants

Conditions That May Affect Hereditary Hyperoxaluria Gene Panel Accuracy

Certain patient-related factors can influence result interpretation:

  • Incomplete clinical or family history details
  • Recent blood transfusion
  • Advanced kidney disease altering clinical correlation
  • Genetic variants outside the tested genes

Diseases That the Hereditary Hyperoxaluria Gene Panel Can Help Detect

  • Primary hyperoxaluria type 1
  • Primary hyperoxaluria type 2
  • Primary hyperoxaluria type 3
  • Inherited oxalate metabolism disorders

References

  1. Cochat P., Rumsby G. (2013). Primary hyperoxaluria. New England Journal of Medicine, 369(7), 649–658. PMID: 23944302
  2. Hopp K., Cogal A.G., Bergstralh E.J., et al. (2015). Phenotype genotype correlations in primary hyperoxaluria. Journal of the American Society of Nephrology, 26(10), 2559–2570. PMID: 25635059
  3. Milliner D.S., Harris P.C., Cogal A.G., Lieske J.C. (2017). Primary hyperoxaluria type 1. GeneReviews, University of Washington. PMID: 20301635

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

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  • Dedicated support team to resolve any delays or queries quickly

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Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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