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3-Methyl Histidine Quantitative Serum Test

₹ 6,510

3-Methyl Histidine Quantitative Serum Test

₹ 6,510

3-Methyl Histidine Quantitative Serum Test

Also Known As :

Report 8th day 06:00 pm

Fasting no

Sample Type edta plasma

Recommended for Male, Female

3-Methyl Histidine - Quantitative, EDTA Plasma**

₹ 6,510

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3 Methyl Histidine Quantitative Serum Test Overview

3-Methyl histidine is a byproduct of skeletal muscle breakdown and is present in the blood in trace amounts. Its levels reflect the rate of skeletal muscle protein breakdown in the body.

The 3 Methyl Histidine Quantitative serum test is a specialised diagnostic tool that measures the levels of 3-Methyl Histidine (3-MH) in the blood. 3-MH is a modified amino acid produced during the breakdown of actin and myosin, the primary contractile proteins found in skeletal muscles.

By quantifying the concentration of 3-MH in the serum, this test provides valuable insights into the rate of muscle protein breakdown and turnover.

The 3 Methyl Histidine Quantitative serum test is particularly useful in assessing muscle catabolism in various physiological and pathological conditions. It can help evaluate muscle injury, monitor the effects of intense physical exercise or strength training, and assess muscle wasting in chronic diseases such as cancer, chronic heart failure, or muscular disorders.

Moreover, this test can be used to study the metabolic changes associated with prolonged bed rest, inactivity, fasting states, or specific dietary patterns.

Reasons for Undergoing the 3 Methyl Histidine Quantitative Serum Test

There are several reasons why a healthcare provider may recommend the 3 Methyl Histidine Quantitative serum test:

To assess muscle protein breakdown, particularly in conditions involving muscle injury, intense physical exercise, or strength training
To monitor muscle catabolism in chronic diseases such as cancer, chronic heart failure, or muscular disorders
To evaluate the effects of prolonged bed rest or inactivity on muscle tissue
To study the metabolic changes associated with fasting states or specific dietary patterns

List of Parameters Considered During the 3 Methyl Histidine Quantitative Serum Test

The primary parameter measured in the 3 Methyl Histidine Quantitative serum test is:

Concentration of 3-MH: This indicates the rate of skeletal muscle protein breakdown. Elevated levels suggest increased muscle catabolism, which can be due to various physiological or pathological conditions such as muscle injury, intense exercise, or chronic diseases.

3-Methyl Histidine Quantitative Serum Test Preparation

Proper preparation is essential for accurate results in 3 Methyl Histidine Quantitative serum test. The following steps should be followed:

Fasting: Patients are typically required to fast overnight for at least 4 hours to minimise the influence of recent dietary intake on the test results.
Specimen Collection: Blood is collected in a green top (sodium heparin) tube. The specimen should be placed on wet ice immediately and centrifuged to separate the plasma within 4 hours if not done immediately. The plasma is then aliquoted into a plastic vial and frozen.
Avoidance of Certain Tubes: Thrombin-activated tubes should not be used for collection.

3-Methyl Histidine Quantitative Serum Test Results & Interpretation

The results of the 3 Methyl Histidine Quantitative serum test are interpreted based on the concentration of 3-MH in the serum:

Normal Levels: The average concentration of 3-MH in human blood plasma is approximately 2.85 micromolar (μM) with a range of 0.0–5.9 μM.
Elevated Levels: Indicate increased muscle protein breakdown, which can be due to muscle injury, intense physical exercise, fasting states, or chronic diseases leading to muscle catabolism.
Interpretation: Results need to be correlated with clinical context, including patient history, physical condition, and other diagnostic findings.

Home Collection for 3 Methyl Histidine Quantitative Serum Test

Metropolis Healthcare offers a convenient home collection service for 3-Methyl Histidine Quantitative serum test, ensuring a comfortable and safe experience for patients. A trained phlebotomist will visit your home to collect the blood sample, maintaining high standards of sample handling and testing accuracy.

This service allows you to receive timely and reliable results without compromising on the quality of diagnostic solutions. Metropolis Healthcare is committed to making healthcare accessible by providing expert diagnostic services conveniently at your doorstep.

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

This test measures the levels of 3-Methyl histidine in your blood.

This test is helpful in diagnosing muscular disorders and assessing their severity. It may be used to

Diagnose muscle atrophy caused by disuse or diseases such as muscular dystrophy.
Monitor the effectiveness of treatment for muscular disorders.
Assess nutritional status and monitor protein intake.

Your doctor may recommend this test if you have

Symptoms suggestive of muscle weakness, such as difficulty climbing stairs or lifting objects.
A previous diagnosis of muscular dystrophy or other muscle disorders.
A history of prolonged immobilisation.
Nutritional deficiencies or malabsorption syndromes that affect protein metabolism.

Low levels of 3-Methyl histidine suggest decreased protein breakdown, while high levels can indicate muscle wasting due to disuse or disease.

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080-4891-1400

Not sure which tests to take? Share your prescription with us and our team will call you.

On submission, our team will contact you to confirm your order.

Your prescription will be securely stored for easy access.

Only specialists will access your prescription.

Upload
Prescription

You can add up to 3 documents in formats: PDF, JPG, PNG

3-Methyl Histidine Quantitative Serum Test

3 Methyl Histidine Quantitative Serum Test Overview

Reasons for Undergoing the 3 Methyl Histidine Quantitative Serum Test

List of Parameters Considered During the 3 Methyl Histidine Quantitative Serum Test

3-Methyl Histidine Quantitative Serum Test Preparation

3-Methyl Histidine Quantitative Serum Test Results & Interpretation

Home Collection for 3 Methyl Histidine Quantitative Serum Test

Frequently asked questions

What does the 3-Methyl Histidine Quantitative Serum Test measure?

Why is the 3-Methyl Histidine Quantitative Serum Test done?

When is the 3-Methyl Histidine Quantitative Serum Test recommended and who should take the test?

What if the results of the 3-Methyl Histidine Quantitative Serum Test are abnormal?

What to expect during the 3-Methyl Histidine Quantitative Serum Test?

What preparations are required before the 3-Methyl Histidine Quantitative Serum Test?

What other tests may be ordered with the 3-Methyl Histidine Quantitative Serum Test?

What is the 3-Methyl Histidine Quantitative Serum Test also known as?

What is muscular dystrophy?

What is 3-Methyl Histidine Quantitative serum test?

Is home sample collection available for the 3-Methyl Histidine Quantitative serum test?

What are the normal levels for the 3-Methyl Histidine Quantitative serum test?

What is a 3-Methyl Histidine Quantitative serum test used for?

How often should I get tested for a 3-Methyl Histidine Quantitative serum test?

What time should I get the 3-Methyl Histidine Quantitative serum test done?

Is fasting required for 3-Methyl Histidine Quantitative serum test?

Are there any other precautions to be taken before getting myself tested for a 3-Methyl Histidine Quantitative serum test?

What parameters are included in the 3-Methyl Histidine Quantitative serum test?

When should the 3-Methyl Histidine Quantitative serum test be done?

How much time does the 3-Methyl Histidine Quantitative serum test take?

How soon can I get the reports for 3-Methyl Histidine Quantitative serum test?

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