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Duchenne muscular dystrophy (DMD) gene analysis
₹ 15000
Duchenne Muscular Dystrophy (DMD) Gene Analysis
₹ 15000 ₹ 15000

Duchenne Muscular Dystrophy (DMD) Gene Analysis

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Duchenne muscular dystrophy (DMD) gene analysis Price

₹ 15000

Brief Details

Preparation
No special preparation required
Also Known As
Duchenne Muscular Dystrophy Gene Panel by NGS
Fasting
Fasting not required
Reporting Time
About 4 weeks
Purpose
To detect genetic changes in the DMD gene associated with Duchenne muscular dystrophy

What is the Duchenne Muscular Dystrophy (DMD) Gene Analysis?

The Duchenne muscular dystrophy gene analysis is a specialised genetic blood test used to identify changes in the DMD gene, which is responsible for producing dystrophin, a protein essential for maintaining healthy muscle structure and function.

This test analyses the DMD gene using advanced Next Generation Sequencing technology from a blood sample. Doctors recommend it to confirm Duchenne muscular dystrophy, a genetic condition that causes progressive muscle weakness beginning in early childhood. The test also helps differentiate Duchenne muscular dystrophy from other muscle disorders with similar symptoms.

What Does the Duchenne Muscular Dystrophy (DMD) Gene Analysis Measure?

This genetic test evaluates the DMD gene to understand the cause of muscle weakness:

  • Detection of disease causing mutations in the DMD gene
  • Identification of genetic changes responsible for dystrophin deficiency
  • Differentiation between Duchenne and Becker muscular dystrophy
  • Support for diagnosis when clinical signs or muscle enzyme tests are inconclusive

Duchenne Muscular Dystrophy (DMD) Gene Analysis: Who Needs It and Why It’s Done

What Symptoms May Call for a Duchenne Muscular Dystrophy (DMD) Gene Analysis?

Your doctor may recommend this test if the following symptoms are present, especially in children:

  • Delayed motor milestones such as late walking
  • Progressive muscle weakness, starting in the legs and hips
  • Difficulty climbing stairs, running, or getting up from the floor
  • Frequent falls or a waddling walking pattern
  • Enlarged calf muscles due to fatty muscle replacement

Who Should Get a Duchenne Muscular Dystrophy (DMD) Gene Analysis?

This test is commonly advised for:

  • Children with unexplained or progressive muscle weakness
  • Individuals with elevated creatine kinase levels
  • Patients suspected to have Duchenne or Becker muscular dystrophy
  • Family members of affected individuals for carrier detection
  • Families seeking genetic counselling or prenatal risk assessment

Why is the Duchenne Muscular Dystrophy (DMD) Gene Analysis Done?

The test confirms or rules out Duchenne muscular dystrophy by identifying genetic changes in the DMD gene, enabling accurate diagnosis, early intervention, and informed long term care planning.

Importance of Duchenne Muscular Dystrophy (DMD) Gene Analysis

DMD gene analysis is essential for establishing a definitive diagnosis of Duchenne muscular dystrophy. Early genetic confirmation allows timely initiation of supportive care, physiotherapy, and emerging treatment options such as corticosteroids or gene based therapies. It also provides critical information for monitoring disease progression, planning future care, and offering genetic counselling to families.

Duchenne Muscular Dystrophy (DMD) Gene Analysis Booking & Reports – Metropolis Healthcare

How to Book the Duchenne Muscular Dystrophy (DMD) Gene Analysis and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Duchenne Muscular Dystrophy (DMD) Gene Analysis, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced molecular diagnostic technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Duchenne Muscular Dystrophy (DMD) Gene Analysis Available Near You?

Yes, Metropolis Healthcare offers home sample collection for Duchenne Muscular Dystrophy (DMD) Gene Analysis. This service saves you time, reduces the need for travel, and ensures professional sample handling while maintaining strict quality standards.

In How Much Time Will I Get Duchenne Muscular Dystrophy (DMD) Gene Analysis Report?

Reports are usually available in about 4 weeks once the sample reaches the laboratory.
Note: Reporting time may vary based on your location.

Where Can I See or Get Duchenne Muscular Dystrophy (DMD) Gene Analysis Results?

You can access your test results through the Metropolis Healthcare website or mobile app by logging in with your credentials. Reports are also shared via email or WhatsApp, and you may collect a physical copy from the Metropolis Lab if required.

Interpreting Duchenne Muscular Dystrophy (DMD) Gene Analysis Results

What Your Duchenne Muscular Dystrophy (DMD) Gene Analysis Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
DMD gene No disease causing variant detected Duchenne muscular dystrophy or Becker muscular dystrophy depending on mutation type Muscle weakness may be due to other genetic or acquired neuromuscular conditions

Understanding Abnormal Duchenne Muscular Dystrophy (DMD) Gene Analysis Test Results

Gene What a Pathogenic Variant May Indicate
DMD Duchenne muscular dystrophy or Becker muscular dystrophy

How Should You Prepare for a Duchenne Muscular Dystrophy (DMD) Gene Analysis?

This genetic test requires minimal preparation from your side:

  • No fasting required: You can eat and drink normally before sample collection
  • Medication information: Inform your doctor about all medicines or supplements you are taking
  • Clinical history: Share details of muscle related symptoms or family history of muscle disorders
  • Test requisition form: Ensure the completed test requisition form and clinical information are provided

How Is a Duchenne Muscular Dystrophy (DMD) Gene Analysis Done? (Step-by-Step Procedure)

The test is carried out using a standard blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible
  • Cleaning: The puncture site is cleaned with antiseptic
  • Sample Collection: A sterile needle is used to collect about 3 to 5 ml of blood into an EDTA vacutainer
  • Completion: The needle is removed, and a bandage is applied
  • Processing: The blood sample is analysed using Next Generation Sequencing to study the DMD gene

Conditions That May Affect Duchenne Muscular Dystrophy (DMD) Gene Analysis Accuracy

Certain patient related factors may influence result interpretation:

  • Incomplete clinical history may limit correlation with genetic findings
  • Variants of uncertain significance may require clinical follow up
  • Family history details are important for accurate interpretation

Diseases That Duchenne Muscular Dystrophy (DMD) Gene Analysis Can Help Detect

  • Duchenne muscular dystrophy
  • Becker muscular dystrophy
  • Inherited dystrophin related muscle disorders
  • Genetic causes of progressive muscle weakness

References

  1. Koenig M., Hoffman E.P., Bertelson C.J., Monaco A.P., Feener C., Kunkel L.M. (1987). Complete cloning of the Duchenne muscular dystrophy gene and preliminary genomic organization. Cell, 50(3), 509–517. PMID: 3607877
  2. Bushby K., Finkel R., Birnkrant D.J., et al. (2010). Diagnosis and management of Duchenne muscular dystrophy, part 1. Lancet Neurology, 9(1), 77–93. PMID: 19945913
  3. Bushby K., Finkel R., Birnkrant D.J., et al. (2010). Diagnosis and management of Duchenne muscular dystrophy, part 2. Lancet Neurology, 9(2), 177–189. PMID: 19945914
  4. Flanigan K.M. (2014). Duchenne and Becker muscular dystrophies. Neurologic Clinics, 32(3), 671–688. PMID: 25037085
  5. Muntoni F., Torelli S., Ferlini A. (2003). Dystrophin and mutations: One gene, several proteins, multiple phenotypes. Lancet Neurology, 2(12), 731–740. PMID: 14636780

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

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Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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