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NextGen CML Panel**
₹ 21000
NextGen CML Panel
₹ 21000 ₹ 21000

NextGen CML Panel

Sample Type 51+ booked in last 3 days

NextGen CML Panel** Price

₹ 21000

Brief Details

Preparation
Haemato-pathological reports with the referring doctor's number is required.
Also Known As
NextGen CML Panel, Chronic Myeloid Leukaemia (CML) Panel
Fasting
Not required
Reporting Time
After 15 Days
Purpose
Helps in diagnosing CML, supports personalised treatment decisions, aids in prognosis assessment and therapy response monitoring

What is a NextGen CML Panel? 

A NextGen CML Panel is an advanced genetic test that uses Next-Generation Sequencing (NGS) technology to examine the genetic makeup of cancer cells in patients with chronic myeloid leukaemia (CML). This sophisticated test analyses your blood or bone marrow sample to identify specific genetic changes that may affect how your treatment works.  

The test helps doctors understand if your leukaemia has developed resistance to current medications and guides them in choosing the most effective treatment for your specific condition. 

What does the NextGen CML Panel measure? 

This CML Panel provides comprehensive genetic information to help personalise your CML treatment: 

  • BCR-ABL1 fusion gene detection - Confirms the presence of this key genetic abnormality that causes CML. 
  • Drug resistance mutations - Identifies genetic changes that may make your cancer resistant to specific medications. 
  • Treatment response markers - Measures genetic factors that predict how well different therapies might work for you. 
  • Disease progression indicators - Detects genetic changes that may signal if your condition is advancing. 
  • Personalised therapy guidance - Provides information to help your doctor select the most suitable treatment approach. 

NextGen CML Panel: Who Needs It and Why It's Done 

What Symptoms May Call for a NextGen CML Panel? 

It is typically ordered for patients already diagnosed with CML rather than based on initial symptoms. However, CML diagnosis often begins when you experience these symptoms: 

  • Persistent fatigue and weakness that doesn't improve with rest. 
  • Unexplained weight loss without trying to lose weight. 
  • Frequent night sweats and fever. 
  • Pain or fullness below your left ribs due to an enlarged spleen. 
  • Easy bruising or bleeding from minor injuries. 
  • Frequent infections that take longer to heal than usual. 

Who should get a NextGen CML Panel? 

This leukaemia blood test is recommended for specific groups of CML patients who need personalised treatment guidance: 

  • Patients with treatment resistance - When your current medication isn't controlling your CML as expected. 
  • Those experiencing disease progression - If your CML is advancing despite ongoing treatment. 
  • Patients requiring treatment changes - When your doctor needs to switch to a different medication. 
  • Newly diagnosed patients - In some cases, to establish a baseline genetic profile for future treatment planning. 
  • Monitoring long-term patients - To track genetic changes in your cancer cells over time. 

Why is a NextGen CML Panel done? 

It is performed to provide precise genetic information that helps your doctor choose the most effective treatment for your specific type of CML. This personalised approach improves your chances of successful treatment and helps avoid medications that may not work for your particular genetic profile. 

Importance of a NextGen CML Panel 

The panel represents a significant advancement in precision medicine for chronic myeloid leukaemia care. This test is clinically important because it transforms how doctors approach treatment decisions. 

By identifying specific genetic mutations that cause drug resistance, the panel eliminates guesswork in treatment selection. Instead of trying different medications through trial and error, your doctor can choose targeted therapies based on your cancer's unique genetic profile.  

This personalised approach saves valuable time, reduces unnecessary side effects, and significantly improves your chances of achieving better treatment outcomes. The test also enables continuous monitoring of how your leukaemia evolves, helping doctors stay ahead of potential resistance developments. 

NextGen CML Panel Booking & Reports – Metropolis Healthcare India 

How to Book a NextGen CML Panel? 

  1. Simple Online Booking 
    Booking can be done through the Metropolis Healthcare App or website. Select NextGen CML Panel, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. 
  1. Safe Home Sample Collection 
    Our trained phlebotomists ensure timely collection of your blood sample while strictly following all safety and hygiene protocols. However, if a bone marrow sample is needed, we receive the sample from your hospital. 
  1. Sample Tracking Updates 
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. 
  1. Accurate Laboratory Testing 
    Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results. 
  1. Quick & Easy Reports 
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app. 

Is home sample collection for NextGen CML Panel available near you? 

Yes, Metropolis Healthcare provides home sample blood collection for the NextGen CML Panel. Our trained phlebotomists follow strict safety protocols while collecting your blood sample in the comfort of your home. This convenient service eliminates travel stress and ensures you receive the same accurate, reliable results you'd get at our pathology lab. However, home sample collection is not available for bone marrow samples, as these are provided by a doctor or hospital. 

How Long Does It Take to Get a NextGen CML Panel Report? 

Reports are usually available after 15 days once the sample reaches the lab. 

Note: Reporting time may vary depending on your location. 

Where can I see or get NextGen CML Panel results? 

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab. 

Interpreting NextGen CML Panel Results 

The following table explains what your NextGen CML Panel results may indicate for different genetic components analysed: 

Parameters 

Normal/Expected 

Abnormal Findings 

Clinical Significance 

BCR-ABL1 Fusion Gene 

Absent in healthy individuals 

Present in CML patients 

Confirms CML diagnosis and guides treatment selection 

Hotspot Mutations 

No resistance mutations detected 

Specific mutations identified 

Indicates drug resistance and need for alternative therapy 

Additional Gene Mutations 

No significant mutations 

Mutations in other cancer-related genes 

May indicate disease progression or transformation 

Gene Expression Levels 

Normal expression patterns 

Altered expression levels 

Helps predict treatment response and prognosis 

Conditions that May Affect NextGen CML Panel Accuracy 

Several factors should be considered when interpreting your NextGen CML Panel results: 

  • Sample quality - Haemolysed, clotted, or insufficient blood samples can affect genetic analysis accuracy. 
  • Recent blood transfusions - May introduce donor genetic material that could interfere with your results. 
  • Concurrent infections - Active infections might affect abnormal blood counts (such as white blood cell abnormalities) and genetic analysis. 
  • Certain medications - Some treatments may influence gene expression patterns in your blood cells. 
  • Sample storage conditions - Improper temperature control during transportation can degrade genetic material. 
  • Timing of sample collection - Recent changes in treatment may temporarily affect genetic markers. 

How is a NextGen CML Panel Done? 

The NextGen CML Panel involves a straightforward blood collection process followed by advanced laboratory analysis: 

  • Sample collection - A healthcare professional draws 6 ml of blood from a vein in your arm using an EDTA tube. In some cases, a bone marrow sample may be collected by your doctor, if recommended. 
  • Sample preparation - Your blood is processed in the laboratory to extract genetic material from white blood cells. 
  • DNA/RNA extraction - Genetic material is carefully isolated and purified for accurate sequencing. 
  • Next-generation sequencing - Advanced technology reads the genetic code of your cancer cells. 
  • Data analysis - Sophisticated computer programs identify mutations and genetic variations. 
  • Report generation - Results are compiled into a comprehensive report for your doctor's review. 

How Should You Prepare for a NextGen CML Panel? 

Preparing for your NextGen CML Panel is simple and requires minimal steps: 

  • No fasting required - You can eat and drink normally before your test. 
  • Continue your medications - Keep taking your prescribed CML medications unless your doctor advises otherwise. 
  • Inform about medications - Tell the healthcare professional about all medicines you're currently taking. 
  • Wear comfortable clothing - Choose a shirt with sleeves that can be easily rolled up for blood collection. 
  • Bring required documents - Have your doctor's prescription and any relevant medical reports ready. 

Diseases that a NextGen CML Panel Can Help Detect 

The NextGen CML Panel is specifically designed to provide comprehensive information about several blood-related conditions: 

  • Chronic Myeloid Leukaemia (CML) - Primary diagnosis and genetic characterisation. 
  • Acute Myeloid Leukaemia - Detection of progression from chronic to acute phase. 
  • Drug-resistant CML - Identification of genetic mutations causing treatment resistance. 
  • CML transformation - Detection of genetic changes indicating disease progression. 
  • Secondary blood cancers - Identification of additional genetic abnormalities that may develop. 
  • Myeloproliferative disorders - Related conditions affecting bone marrow and blood cell production. 

NextGen CML Panel/Packages that You Can Book With Metropolis Healthcare 

The following table shows related leukaemia testing options available at Metropolis Healthcare: 

Test/Package Name 

Purpose/Highlights 

Leukaemia Characterisation Panel for CLPD 

Comprehensive analysis for chronic lymphoproliferative disorders 

Leukaemia - Chronic Lymphoproliferative Disorder Test 

Specific testing for chronic lymphocytic leukaemia and related health conditions 

Leukaemia - Acute Leukaemia Panel, Bone Marrow Test 

Detailed analysis of acute leukaemia using bone marrow samples 

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Choose precision On time, every time!

Precision
  • 98% on time collections with a 60 minutes promise
  • Real-time tracking of phlebotomist arrival and report generation
  • Fully digital report delivery—view from mobile or desktop instantly
  • Continuous monitoring of turnaround times to ensure accuracy and speed
  • Dedicated support team to resolve any delays or queries quickly

Why Metropolis Healthcare?

Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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About Us

Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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