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Combine screening of Pre-eclampsia & Trisomies
₹ 3,710
Combine screening of Pre-eclampsia & Trisomies
₹ 3,710
Booked 51+ booked in last 3 days

Combine screening of Pre-eclampsia & Trisomies

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Combine screening of Pre-eclampsia & Trisomies, Serum
₹ 3,710

PreEclapmsia (PE) is a pregnancy condition characterized by hypertension occurring after 20 weeks of pregnancy together with proteinurea. PE if not diagnosed and treated early increases the chances of pre-term labour and related complications. Apart from USG and clinical examination, combined pre-eclampsia screening includes certain blood marker tests performed to screen the patient for the risk of PE as well as chromosomal abnormalities. The risk is assessed using a software dependent statistical analysis of risk score done using Foetal Medicine Foundation(FMF) approved assays. For better reliability of results, it is advised to carry out analysis between 11 and 13 weeks.

Written by - Dr. Shibani R, Medical Writer, Medical Affairs

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Combined screening of Preeclampsia and trisomy measures the Free beta HCG, PAPPa, PLGF and NT levels in the blood serum.

  • The test is used to screen for patients at risk of developing PreEclampsia (PE) during pregnancy.
  • The test if done early helps to prevent PE associated complications later in the pregnancy.
  • Helps the clinician to start the pregnant woman on timely treatment and ensures close monitoring throughout the pregnancy.
  • Helps to monitor cases at risk for foetal abnormalities, intrauterine growth restrictions etc.
  • Helps to detect and rule out chromosomal anomalies and trisomies.
  • Helps in the detection of neural tube defects.

  • Pregnant women at risk or suspected to have foetal anomalies should ideally undergo combined PE screening between 11 and 13 weeks of pregnancy.
  • Pregnant women with previous history of PE or adverse pregnancy outcomes.
  • Those with family history of co-morbidities like hypertension, type 1 or Type 2 diabetes mellitus, obesity, thyroid disorders, kidney disorders etc.
  • Those with an immediate family history of chromosomal abnormalities, Down’s syndrome or Edward syndrome should undergo the screening.

 

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. The maternal clinical history, USG reports, TRF details and other details are mandatory.

 

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