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Familial hemiplegic migraine gene panel
₹ 19400
Familial Hemiplegic Migraine Gene Panel
₹ 19400 ₹ 19400

Familial Hemiplegic Migraine Gene Panel

Sample Type 51+ booked in last 3 days
Precaution
Sample Type
Swab
Precaution
Fasting
Yes
Precaution
Report
Within 4 Weeks

Familial hemiplegic migraine gene panel Price

₹ 19400

Brief Details

Preparation
No special preparation required
Also Known As
Familial Hemiplegic Migraine Gene Panel by NGS
Fasting
Fasting not required
Reporting Time
About 4 weeks
Purpose
To detect genetic changes associated with familial hemiplegic migraine and related inherited migraine disorders

What is the Familial Hemiplegic Migraine Gene Panel?

The familial hemiplegic migraine gene panel is a specialised genetic blood test used to identify inherited causes of familial hemiplegic migraine, a rare form of migraine that runs in families. This condition is characterised by severe migraine attacks accompanied by temporary weakness or paralysis on one side of the body.

The test analyses specific genes from a blood sample using advanced Next Generation Sequencing technology. It helps confirm a genetic diagnosis and distinguish familial hemiplegic migraine from other neurological conditions that can mimic stroke.

What Does the Familial Hemiplegic Migraine Gene Panel Measure?

This genetic test evaluates genes involved in brain signalling and ion channel function:

  • Detection of disease causing genetic variants linked to familial hemiplegic migraine
  • Identification of the specific gene responsible for hemiplegic migraine episodes
  • Differentiation from non genetic migraine types and stroke like conditions
  • Support for accurate diagnosis when clinical symptoms overlap with other neurological disorders

Familial Hemiplegic Migraine Gene Panel: Who Needs It and Why It’s Done

What Symptoms May Call for a Familial Hemiplegic Migraine Gene Panel?

Your doctor may recommend this test if you experience:

  • Severe migraine attacks with temporary weakness or paralysis on one side of the body
  • Migraine episodes accompanied by visual disturbances, speech difficulty, or confusion
  • Neurological symptoms that closely resemble stroke but fully resolve
  • Recurrent migraine attacks beginning at a young age
  • Similar migraine symptoms in close family members

Who Should Get a Familial Hemiplegic Migraine Gene Panel?

This test is recommended for:

  • Individuals with suspected familial hemiplegic migraine
  • Patients with migraine attacks associated with motor weakness
  • People with a strong family history of hemiplegic migraine
  • Individuals where stroke or other neurological causes have been ruled out
  • Families seeking genetic counselling and recurrence risk assessment

Why is the Familial Hemiplegic Migraine Gene Panel Done?

The test helps confirm a genetic diagnosis of familial hemiplegic migraine, allowing appropriate treatment planning, risk assessment, and long term management.

Importance of Familial Hemiplegic Migraine Gene Panel

This gene panel plays an important role in accurately diagnosing familial hemiplegic migraine. A confirmed genetic diagnosis helps avoid unnecessary emergency interventions, guides preventive migraine treatment, and provides reassurance when stroke like symptoms occur. It also supports genetic counselling and helps assess risks for family members.

Familial Hemiplegic Migraine Gene Panel Booking & Reports – Metropolis Healthcare

How to Book the Familial Hemiplegic Migraine Gene Panel and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the Familial Hemiplegic Migraine Gene Panel, choose a convenient time slot, and provide your address for a blood test at home. You may also visit a nearby Metropolis Lab if you prefer in person sample collection.
  2. Safe Home Sample Collection
    Trained phlebotomists collect your blood sample while strictly following safety and hygiene protocols.
  3. Sample Tracking Updates
    You receive updates at every stage, from sample collection to testing, through the Metropolis Healthcare platform.
  4. Accurate Laboratory Testing
    Your sample is processed at NABL and CAP accredited laboratories using advanced molecular diagnostic technology.
  5. Quick and Easy Reports
    Your reports are shared via email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or app.

Is Home Sample Collection for Familial Hemiplegic Migraine Gene Panel Available Near You?

Yes, Metropolis Healthcare offers home sample collection for the Familial Hemiplegic Migraine Gene Panel. This service saves you time, reduces the need for travel, and ensures professional sample handling while maintaining strict quality standards.

In How Much Time Will I Get Familial Hemiplegic Migraine Gene Panel Report?

Reports are usually available in about 4 weeks once the sample reaches the laboratory.
Note: Reporting time may vary based on your location.

Where Can I See or Get Familial Hemiplegic Migraine Gene Panel Results?

You can access your test results through the Metropolis Healthcare website or mobile app using your credentials. Reports are also shared via email or WhatsApp, and you may collect a physical copy from the Metropolis Lab if required.

Interpreting Familial Hemiplegic Migraine Gene Panel Results

What Your Familial Hemiplegic Migraine Gene Panel Results May Indicate

Parameter Expected Finding Pathogenic Variant Detected May Indicate No Variant Detected May Indicate
ATP1A2, CACNA1A, PRRT2, SCN1A No disease causing variant detected Familial hemiplegic migraine or a related inherited migraine disorder Symptoms may be due to non genetic migraine types or genes not included in this panel

Understanding Abnormal Familial Hemiplegic Migraine Gene Panel Test Results

Gene What a Pathogenic Variant May Indicate
CACNA1A Familial hemiplegic migraine type 1 with severe migraine and neurological symptoms
ATP1A2 Familial hemiplegic migraine type 2 often associated with aura and weakness
SCN1A Hemiplegic migraine sometimes associated with seizure susceptibility
PRRT2 Migraine with paroxysmal neurological symptoms and episodic attacks

How Should You Prepare for a Familial Hemiplegic Migraine Gene Panel?

This genetic test requires minimal preparation from your side:

  • No fasting required: You can eat and drink normally before sample collection
  • Medication information: Inform your doctor about all medicines you are taking
  • Clinical history: Share details of migraine pattern, neurological symptoms, and family history
  • Test requisition form: Ensure the completed test requisition form and clinical information are provided

How Is a Familial Hemiplegic Migraine Gene Panel Done? (Step-by-Step Procedure)

The test is performed using a standard blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible
  • Cleaning: The puncture site is cleaned with antiseptic
  • Sample Collection: A sterile needle is used to collect about 3 to 5 ml of blood into an EDTA vacutainer
  • Completion: The needle is removed, and a bandage is applied
  • Processing: The blood sample is analysed using Next Generation Sequencing to study the listed genes

Conditions That May Affect Familial Hemiplegic Migraine Gene Panel Accuracy

Certain patient related factors may influence result interpretation:

  • Incomplete clinical history may limit correlation with genetic findings
  • Variants of uncertain significance may require follow up and specialist interpretation
  • Genetic results should be interpreted alongside neurological assessment and imaging findings

Diseases That Familial Hemiplegic Migraine Gene Panel Can Help Detect

  • Familial hemiplegic migraine type 1
  • Familial hemiplegic migraine type 2
  • Genetic migraine syndromes with neurological deficits
  • Inherited migraine disorders mimicking stroke

References

  1. Ophoff R.A., Terwindt G.M., Vergouwe M.N., et al. (1996). Familial hemiplegic migraine and episodic ataxia type 2 are caused by mutations in the calcium channel gene CACNA1A. Cell, 87(3), 543–552. PMID: 8898206
  2. De Fusco M., Marconi R., Silvestri L., et al. (2003). Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. Nature Genetics, 33(2), 192–196. PMID: 12539049
  3. Russell M.B., Ducros A. (2011). Sporadic and familial hemiplegic migraine: Pathophysiological mechanisms, clinical characteristics, diagnosis, and management. The Lancet Neurology, 10(5), 457–470. PMID: 21458378
  4. Gardner K., Barmherzig R. (2019). Hemiplegic migraine: A review of diagnostic criteria, management, and pathophysiology. Current Pain and Headache Reports, 23(4), 28. PMID: 30905095

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

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  • Real-time tracking of phlebotomist arrival and report generation
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  • Dedicated support team to resolve any delays or queries quickly

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Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

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