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Autoimmune Dementia
₹ 40000
Autoimmune Dementia Profile
₹ 40000 ₹ 40000

Autoimmune Dementia Profile

Sample Type 51+ booked in last 3 days

Autoimmune Dementia Price

₹ 40000

Brief Details

Preparation
No special preparation required
Also Known As
Autoimmune Dementia Panel, Neural Autoantibody Panel
Fasting
Not required
Reporting Time
Next Day: 5:00 PM
Purpose
Identifies autoimmune and paraneoplastic causes of dementia and related neurodegenerative syndromes

What is an Autoimmune Dementia Profile Test? 

An autoimmune dementia profile test is a specialised blood test designed to identify treatable causes of dementia and cognitive decline. Unlike common forms of dementia such as Alzheimer's disease, this test focuses on detecting autoimmune conditions that can mimic dementia symptoms. 

The test helps detect specific autoantibodies that mistakenly attack your brain and nerve cells, leading to cognitive dysfunction and neurological disorders that may be reversible with proper treatment. 

What does the Autoimmune Dementia Profile Test measure? 

This comprehensive test examines your blood for specific neural autoantibodies that can cause brain inflammation and cognitive symptoms: 

  • NMDAR antibodies: Often linked to psychiatric symptoms, memory loss, and seizures 
  • LGI1 antibodies: Associated with memory problems and specific types of seizures 
  • CASPR2 antibodies: Connected to cognitive changes, nerve pain, and movement disorders 
  • GABA-B receptor antibodies: Related to rapid memory loss and seizures 
  • Paraneoplastic antibodies (Anti-Hu, Anti-Yo, Anti-Ri): Associated with cancer-related neurological symptoms 
  • Other neural antibodies: Including AMPAR, DPPX, and IgLON5 antibodies that affect brain function and vascular dementia 

Autoimmune Dementia Profile Test: Who Needs It and Why It's Done 

What Symptoms May Call for an Autoimmune Dementia Profile Test? 

Your doctor may recommend this test if you experience rapid cognitive decline with unusual features: 

  • Rapidly progressive dementia: Sudden decline in memory and thinking skills over weeks or months 
  • Psychiatric disturbances: New onset confusion, agitation, hallucinations, or severe mood swings 
  • New seizures: Seizures that cannot be explained by other causes 
  • Movement disorders: Unusual involuntary movements, muscle twitching, or stiffness 
  • Fluctuating symptoms: Having alternating "good days" and "bad days" with varying symptom severity 

Who should get an Autoimmune Dementia Profile Test?  

This specialised test is recommended for specific groups rather than routine screening: 

  • Patients with atypical dementia: Those whose symptoms appeared suddenly or progressed unusually fast 
  • Individuals with unexplained cognitive decline: When standard tests don't show clear causes like stroke or typical Alzheimer's disease patterns 
  • People with autoimmune history: Those with personal or family history of autoimmune conditions 
  • Patients with neuropsychiatric symptoms: Those showing combination of cognitive, psychiatric, and neurological symptoms 

Why is an Autoimmune Dementia Profile Test done? 

The test is performed to identify potentially reversible forms of dementia that can be treated with immunotherapy, distinguishing them from progressive health conditions like Alzheimer's disease. 

Importance of an Autoimmune Dementia Profile Test 

This test holds significant clinical importance because it can completely change your diagnosis and treatment approach. Early identification of autoimmune causes enables targeted immunotherapy treatments that may significantly improve or even reverse cognitive symptoms. 

The test guides doctors away from symptom management towards addressing the root autoimmune cause, potentially transforming what might seem like an untreatable progressive dementia into a manageable condition with specific therapies. 

Autoimmune Dementia Profile Test Booking & Reports – Metropolis Healthcare India 

How to Book an Autoimmune Dementia Profile Test? 

  1. Simple Online Booking 
    Booking can be done through the Metropolis Healthcare app or website. Select Autoimmune Dementia Profile Test, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. 
  1. Safe Home Sample Collection 
    Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols. 
  1. Sample Tracking Updates 
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. 
  1. Accurate Laboratory Testing 
    Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results. 
  1. Quick & Easy Reports 
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app. 

Is home sample collection for Autoimmune Dementia Profile Test available near you?  

Yes, home blood sample collection is available for the autoimmune dementia profile test. Our trained phlebotomists follow strict protocols to collect your blood sample in the comfort of your home. With Metropolis Healthcare's extensive network of over 10,000 touchpoints across India, we ensure reliable sample collection and accurate testing. This service eliminates the need for hospital visits while maintaining the highest standards of safety and precision for your autoimmune dementia screening. 

How Long Does It Take to Get an Autoimmune Dementia Profile Test Report?  

Reports are usually available the next day by 5:00 PM once the sample reaches the pathology lab. 

Note: Reporting time may vary depending on your location. 

Where can I see or get Autoimmune Dementia Profile Test results? 

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare app to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab. 

Interpreting Autoimmune Dementia Profile Test Results 

What Your Autoimmune Dementia Profile Test Results May Indicate 

The following table outlines some essential biomarkers to help interpret your antibody test results: 

Parameter 

Normal Range 

Positive Result 

Negative Result 

Anti-Hu (ANNA-1) 

Negative/Not Detected 

May indicate paraneoplastic neurological syndrome, often associated with lung cancer 

Normal - no autoimmune activity detected 

Anti-Ri (ANNA-2) 

Negative/Not Detected 

May suggest paraneoplastic syndrome, commonly linked with breast cancer or gynaecological tumours 

Normal - no autoimmune activity detected 

Anti-Yo (PCA-1) 

Negative/Not Detected 

May indicate cerebellar degeneration, often associated with ovarian or breast cancer 

Normal - no autoimmune activity detected 

NMDA Receptor Antibody 

Negative/Not Detected 

May suggest autoimmune encephalitis with psychiatric and memory symptoms 

Normal - no autoimmune activity detected 

LGI1 Antibody 

Negative/Not Detected 

May indicate limbic encephalitis with memory problems and specific seizures 

Normal - no autoimmune activity detected 

Conditions that May Affect Autoimmune Dementia Profile Test Accuracy 

Several factors can influence your autoimmune dementia profile test results and should be discussed with your doctor: 

  • Immunosuppressive medications: Steroids and other immune-suppressing drugs may reduce antibody levels 
  • Recent immunotherapy treatments: Previous treatments may affect current antibody concentrations 
  • Timing of sample collection: Antibody levels may fluctuate during different stages of the condition 
  • Concurrent infections: Active infections might influence immune system responses 
  • Blood sample quality: Haemolysed, lipemic, or improperly stored samples can affect results 
  • Laboratory processing conditions: Temperature variations during transport may impact antibody stability 

How is an Autoimmune Dementia Profile Test Done? 

The autoimmune dementia profile test involves a straightforward blood collection process performed by trained professionals: 

  • Your arm is cleaned with an antiseptic solution at the puncture site 
  • An elastic band is tied around your upper arm to make veins more visible 
  • A sterile needle is inserted into a vein to draw approximately 3ml of blood into a special gel vacutainer 
  • The blood sample is processed to separate serum for antibody testing 
  • Advanced immunofluorescence assay and immunoblot techniques detect specific neural antibodies 

How Should You Prepare for an Autoimmune Dementia Profile Test? 

Preparing for your autoimmune dementia profile test is simple and requires minimal preparation: 

  • No fasting required: You can eat and drink normally before the test 
  • Continue medications: Take your regular medications unless specifically advised otherwise by your doctor 
  • Inform about treatments: Tell your doctor about any recent immunotherapy or steroid treatments 
  • Stay hydrated: Drink adequate water to make blood collection easier 
  • Wear comfortable clothing: Choose clothing that allows easy access to your arm 

Diseases that an Autoimmune Dementia Profile Test Can Help Detect 

This comprehensive test can help identify several serious neurological conditions that may present with dementia-like symptoms: 

  • Autoimmune encephalitis: Brain inflammation caused by immune system attacks 
  • Paraneoplastic neurological syndromes: Cancer-related neurological symptoms 
  • Limbic encephalitis: Inflammation affecting memory and emotional centres of the brain 
  • Cerebellar degeneration: Progressive loss of balance and coordination functions 
  • Anti-NMDAR encephalitis: Severe autoimmune brain inflammation with psychiatric symptoms 
  • Rapidly progressive dementia: Fast-onset cognitive decline with treatable causes 

Autoimmune Dementia Profile Test/Packages that You Can Book With Metropolis Healthcare 

Here are related tests and packages that complement your autoimmune dementia screening: 

Test/Package Name 

Purpose/Highlights 

Whole Exome Sequencing 

Comprehensive genetic test sequencing all protein-coding genes & mitochondrial genes to aid in diagnosing genetic disorders and rare diseases 

Test/Package Name 

Purpose/Highlights 

Pre-Transplant Workup Panel 

Comprehensive evaluation for organ transplant candidates 

NextGen HRR Gene Panel 

Advanced genetic testing for hereditary cancer risks 

DNA Paternity 16 Markers 

Paternity testing using 16 genetic markers 

Frequently asked questions

Find quick answers to the most common questions about health tests, bookings, and reports.

Regular exercise, a balanced diet, avoiding smoking, maintaining a healthy weight, and managing stress all help reduce heart disease risk.

Common signs include irritability, trouble sleeping, headaches, difficulty concentrating, and muscle tension.

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Ratings & Reviews

We're satisfying our customers every day since 1980.

Morning given the samples in Ayanavaram branch got the report by 12.30pm it's fast and efficient delivery by mail and want to tell about the staff they are very professional and friendly definitely I will recommend my friends and family to metropolis labs

Prabhu Gopalakrishnan. 5

The Home Service was excellent. Medical Technician took samples at 7:00am and returned at 9:30 after breakfast to take further samples. The results were sent by email at 6pm. The whole experience was excellent, professional and well organised. Will certainly recommend the home service for convenience

Chris Bessell 5

Excellent service - I was able to request services late at night (9pm) and the technician was at my door at 7:30am the next morning. The services were highly affordable and convenient. I live in the US and the US could learn a lot from Metropolis!!!

Sharmila Vaishnav. 5

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Very good staff, excellent execution of samples, timely results even before promised time. professional and well organised. Will certainly recommend the home service for convenience

Ishwarakrishnan. 4

Choose precision On time, every time!

Precision
  • 98% on time collections with a 60 minutes promise
  • Real-time tracking of phlebotomist arrival and report generation
  • Fully digital report delivery—view from mobile or desktop instantly
  • Continuous monitoring of turnaround times to ensure accuracy and speed
  • Dedicated support team to resolve any delays or queries quickly

Why Metropolis Healthcare?

Metropolis has been present for over 40 years in the market.

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

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About Us

Metropolis Healthcare is a leading diagnostic service provider in India. We are a team of dedicated professionals committed to ensuring you and your family receive the most accurate and timely healthcare solutions. We believe in making health care accessible, affordable and evidence-based. Our expert panel are equipped with the latest technology and manned by a certified team of over 4000+ technicians.

In diagnostic services, we have more than three decades of experience servicing diverse stakeholders health advantage packages for men, women and seniors, genetic fitness & corporation in over 650+ tests like Oncology, Neurology, Gynaecology, Haematology, and many more. Our diagnostic services are located in leading doctors and clinics and serve over 15+ cities in India.

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