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Metropolis Healthcare
Last Updated July 23, 2026
Medicine
Diclogem Tablet: Uses, Dosage and Side Effects

Pain and inflammation can make routine movement, work, and rest difficult. Your doctor may prescribe Diclogem tablet for short-term relief from conditions such as arthritis, back pain, dental pain, or a muscle injury.

Diclogem is a prescription pain-relieving medicine. You should take it only in the dose and for the duration advised by your doctor. Using it in excess or combining it with similar painkillers can harm your stomach, liver, kidneys, or heart.

What Is Diclogem Tablet?

Diclogem tablet is a combination medicine used to reduce pain, inflammation, swelling, and fever.

The standard Diclogem tablet commonly contains diclofenac and paracetamol. However, different variants may have different ingredients. For example, products with MR or SP in their names may include a muscle relaxant or another medicine for swelling.

Always check the composition printed on your medicine strip. Do not treat different Diclogem variants as interchangeable.

Diclofenac and Paracetamol Composition

A commonly available Diclogem tablet contains:

  • Diclofenac sodium 50 mg
  • Paracetamol 325 mg

Diclofenac is a non-steroidal anti-inflammatory drug, also called an NSAID. It reduces pain, inflammation, and swelling.

Paracetamol is an analgesic and antipyretic. It reduces pain and can help lower fever.

The combination may offer better relief than either medicine alone in selected painful conditions. However, it also combines their safety risks. Medical supervision is important.

How Diclogem Tablet Works

Pain and swelling are partly caused by substances called prostaglandins. Diclofenac blocks enzymes involved in producing these substances. This helps reduce inflammation, tenderness, and pain.

Paracetamol acts mainly within the central nervous system. It changes how your body responds to pain and helps control an increased body temperature.

Diclogem provides symptomatic relief. It does not cure arthritis, repair an injury, or treat the underlying cause of persistent pain.

Diclogem Tablet Uses

Common Diclogem tablet uses include short-term relief from:

  • Joint pain and inflammation
  • Arthritis-related pain
  • Back, neck, and shoulder pain
  • Muscle strains and sprains
  • Dental pain
  • Pain after selected procedures
  • Menstrual pain
  • Pain and fever associated with certain illnesses

Your doctor will consider the cause and severity of your pain before prescribing it.

Arthritis and Joint Pain

Diclogem may reduce pain, swelling, and stiffness caused by osteoarthritis, rheumatoid arthritis, or other inflammatory joint conditions.

It may help you move more comfortably, but it does not slow the underlying disease. Long-term arthritis management may also involve exercise, weight management, physiotherapy, and condition-specific medicines.

Oral NSAIDs should generally be used at the lowest effective dose for the shortest possible duration. This reduces the risk of stomach, kidney, liver, and cardiovascular complications.

Musculoskeletal and Post-Operative Pain

Diclogem may be prescribed for musculoskeletal pain caused by a strain, sprain, back problem, sports injury, or soft tissue inflammation.

It may also be used for short-term post-operative pain when your treating doctor considers it suitable. Pain after surgery can have different causes, so do not start Diclogem without checking with your surgical team.

Persistent pain, increasing swelling, loss of movement, numbness, or weakness requires medical assessment.

Benefits of Diclogem Tablet

When prescribed appropriately, Diclogem may:

  • Reduce mild to moderate pain
  • Control inflammation and swelling
  • Ease stiffness linked to joint or muscle conditions
  • Support movement during short-term recovery
  • Reduce fever when it occurs with pain
  • Help you return to daily activities more comfortably

The medicine should support recovery rather than replace rest, rehabilitation, or treatment of the underlying condition.

Diclogem Dosage and Administration

There is no single dosage that is appropriate for everyone. Your dose depends on the exact composition, your age, condition, medical history, and other medicines.

Situation

General Administration Advice

Important Precaution

Short-term pain

Take the prescribed number of tablets at the advised times

Do not increase the dose if pain continues

Arthritis pain

Use only for the duration advised by your doctor

Daily or prolonged use needs medical review

Post-operative pain

Follow the instructions from your treating team

Do not combine it with another NSAID

Missed dose

Take it when remembered unless the next dose is close

Never take two doses together

Swallow Diclogem whole with water. Taking it with or immediately after food may reduce stomach irritation.

Do not crush or chew the tablet unless the product information specifically permits it. Take it at consistent times when your doctor has prescribed more than one daily dose.

Check all cold, fever, and pain medicines before taking them. Many contain paracetamol, diclofenac, ibuprofen, or another NSAID. Combining these products can cause an accidental overdose.

Diclogem Tablet Side Effects

Not everyone experiences side effects. Common effects may include:

Speak to your doctor if these effects persist or worsen.

Serious side effects are less common, but they require prompt attention. Stop the medicine and seek urgent medical care if you experience:

  • Vomiting blood
  • Black or tar-like stools
  • Severe or persistent stomach pain
  • Chest pain or sudden breathlessness
  • Weakness on one side of your body
  • Reduced urine output or marked swelling
  • Facial swelling or difficulty breathing
  • A widespread rash, blisters, or peeling skin

These symptoms may indicate gastrointestinal bleeding, a cardiovascular event, kidney injury, an allergic reaction, or a serious skin reaction.

Precautions and Warnings

Tell your doctor before taking Diclogem if you have:

Older adults may be more vulnerable to stomach bleeding, kidney problems, and other NSAID-related complications.

Diclofenac is not suitable for some people with established cardiovascular disease. It can also cause fluid retention and may worsen blood pressure, kidney function, or heart failure.

Avoid Diclogem during pregnancy unless your doctor specifically prescribes it. NSAIDs such as diclofenac can affect the pregnancy and unborn baby, particularly after 20 weeks. They are contraindicated during the final trimester.

Ask your doctor before using it while breastfeeding or when trying to conceive.

Signs of Liver Problems

Both diclofenac and paracetamol can affect your liver. The risk increases with excessive doses, prolonged use, liver disease, or alcohol consumption.

Stop taking the medicine and contact your doctor if you notice:

Paracetamol overdose can cause delayed and serious liver damage even when you initially feel well. Seek emergency medical care immediately if you take more than prescribed.

Diclogem Drug Interactions

Tell your doctor about every medicine, supplement, and herbal product you use.

Diclogem may interact with:

  • Aspirin, ibuprofen, naproxen, and other NSAIDs
  • Blood thinners such as warfarin
  • Antiplatelet medicines
  • Corticosteroids
  • Certain antidepressants
  • Diuretics and medicines for hypertension
  • Lithium
  • Methotrexate
  • Ciclosporin or tacrolimus
  • Other medicines containing paracetamol
  • Regular or excessive alcohol

Some combinations increase the risk of bleeding. Others can affect blood pressure, kidney function, liver function, or medicine levels.

Do not stop an essential medicine without medical advice. Ask your doctor or pharmacist to review the combination.

Most people using Diclogem for a brief period do not need repeated tests. Monitoring may be advised if you require longer treatment or have existing health risks.

Your doctor may recommend:

These investigations can help identify adverse effects early and guide safer pain management.

Frequently Asked Questions

Is Diclogem a Painkiller or an Antibiotic?

Diclogem is a painkiller and anti-inflammatory medicine. It is not an antibiotic and cannot treat a bacterial infection.

How Quickly Does Diclogem Relieve Pain?

Some people may begin to feel relief within an hour. The response depends on the condition, pain severity, tablet formulation, food intake, and individual health factors.

Do not take an extra dose if relief is not immediate.

Can Diclogem Be Taken With Food?

Yes. Taking Diclogem with or after food may reduce indigestion and stomach irritation. Food does not remove the risk of ulcers or gastrointestinal bleeding.

Is It Safe to Take Diclogem Every Day?

Daily use may be appropriate only when prescribed and monitored by your doctor. Regular NSAID use can increase stomach, kidney, liver, blood pressure, and cardiovascular risks.

You should use the lowest effective dose for the shortest possible time.

Can Diclogem Affect the Liver?

Yes. Diclogem contains paracetamol and diclofenac, both of which can affect liver function. The risk is greater with excessive doses, prolonged use, liver disease, alcohol, or other paracetamol-containing medicines.

Seek immediate care after a suspected overdose, even when you feel well.

Conclusion

Diclogem tablet can provide short-term relief from arthritis pain, musculoskeletal pain, inflammation, and selected post-operative discomfort. Safe use depends on confirming the exact composition, following your prescription, and avoiding duplicate pain medicines.

Persistent pain or frequent painkiller use may require further assessment. If your doctor recommends monitoring, Metropolis Healthcare offers liver function tests, kidney function tests, complete blood counts, and a wide range of speciality investigations.

Metropolis Healthcare provides more than 4,000 tests through NABL and CAP accredited laboratories. You can also choose preventive full body checkups to stay informed about important health markers. With expert pathologists, reliable reports, quick turnaround times, and home sample collection across more than 10,000 touchpoints, managing your health becomes more convenient. You can book through the website, app, phone, or WhatsApp.

References

  1. Dexcel Pharma Ltd. Diclofenac Sodium Dexcel SR 75 mg Prolonged-Release Tablets: Summary of Product Characteristics. Electronic Medicines Compendium. Revised 2026.
  2. Rivopharm UK Ltd. Paracetamol 500 mg Tablets: Summary of Product Characteristics. Electronic Medicines Compendium. Revised 2025.
  3. Medicines and Healthcare Products Regulatory Agency. Non-Steroidal Anti-Inflammatory Drugs: Potential Risks Following Prolonged Use After 20 Weeks of Pregnancy. Drug Safety Update. 202
  4. National Institute for Health and Care Excellence. Osteoarthritis in Over 16s: Diagnosis and Management. NICE Guideline NG226. 2022.
  5. National Institute for Health and Care Excellence. Low Back Pain and Sciatica in Over 16s: Assessment and Management. NICE Guideline NG59. Updated 2020.

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