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Hifenac P Tablet is a prescription pain-relief medicine used for selected painful and inflammatory conditions. It combines aceclofenac and paracetamol to reduce pain, swelling and fever.
You should take Hifenac P only in the dose and for the duration prescribed by your doctor. Incorrect or prolonged use can affect your stomach, liver, kidneys or heart.
What Is Hifenac P Tablet?
Hifenac P Tablet is an analgesic and anti-inflammatory medicine commonly prescribed for short-term relief from pain and stiffness affecting your joints, muscles, back or teeth.
The commonly marketed tablet contains aceclofenac 100 mg and paracetamol 325 mg. Check the strip before taking it because similarly named products may have different ingredients or strengths.
Hifenac P is not an opioid and is not considered habit-forming. However, it is not suitable for everyone.
Aceclofenac and Paracetamol Combination
Aceclofenac is a non-steroidal anti-inflammatory drug, also called an NSAID. It reduces pain and inflammation.
Paracetamol is an analgesic and antipyretic. It reduces pain and can lower fever. Since Hifenac P contains both medicines, you must account for both ingredients when checking other tablets.
How Hifenac P Tablet Relieves Pain
Inflamed or injured tissues produce chemicals called prostaglandins. These contribute to pain, swelling and fever.
Aceclofenac reduces prostaglandin production by inhibiting cyclooxygenase enzymes. Paracetamol mainly acts within the central nervous system to reduce pain perception and control fever.
Hifenac P provides symptom relief. It does not cure arthritis, repair an injury or address every underlying cause of pain.
Uses of Hifenac P Tablet
Common Hifenac P Tablet uses include short-term relief from:
- Joint pain and stiffness
- Pain linked with Osteoarthritis
- Pain and inflammation associated with Rheumatoid Arthritis
- Ankylosing spondylitis
- Back and neck pain
- Muscle aches, sprains and strains
- Dental pain
- Ear or throat pain when prescribed as part of treatment
Your doctor will decide whether this combination is appropriate based on the cause of your pain and your medical history.
Osteoarthritis and Rheumatoid Arthritis
Osteoarthritis can cause pain and stiffness as joint cartilage wears down. Rheumatoid Arthritis is an autoimmune condition that causes joint inflammation.
Hifenac P may reduce symptoms during a flare or while another treatment takes effect. It does not stop joint damage in Rheumatoid Arthritis or reverse Osteoarthritis. Your broader treatment may include exercise, physiotherapy, weight management or disease-modifying medicines.
Dental, Back and Musculoskeletal Pain
A doctor may prescribe Hifenac P for acute toothache, back pain, sprains, strains or other musculoskeletal pain. Its anti-inflammatory action can help when swelling contributes to your symptoms.
Pain relief should not delay treatment of the cause. Dental pain may need dental care, while persistent back pain may require examination or physiotherapy.
Hifenac P Dosage Guidelines
The correct dose depends on your age, symptoms, health conditions and other medicines. This table gives general guidance only.
Situation | General Guidance |
Usual adult use | Many prescriptions use one tablet once or twice daily. Follow the exact frequency written by your doctor. |
When to take it | Take it with or just after food and a glass of water. |
How to take it | Swallow it whole. Do not crush or chew it unless your doctor or pharmacist says you can. |
Duration | Use the lowest effective dose for the shortest possible time. |
Missed dose | Take it when remembered unless the next dose is due soon. Never take two doses together. |
Overdose | Seek urgent medical care, even if you feel well. Paracetamol overdose can cause delayed liver injury. |
Children | Do not give it to a child unless a paediatrician has prescribed it. |
Do not combine Hifenac P with another paracetamol medicine or an NSAID such as ibuprofen, diclofenac or naproxen unless your doctor approves it.
Side Effects of Hifenac P Tablet
Hifenac P side effects may include:
- Nausea
- Indigestion or heartburn
- Stomach pain
- Diarrhoea
- Vomiting
- Dizziness or drowsiness
- Reduced appetite
- Increased liver enzymes
- Skin rash
- Fluid retention
Mild effects may settle after a short period. Contact your doctor if they persist, worsen or interfere with eating and drinking.
Stomach-Related Effects: Nausea, Indigestion and Ulcers
Aceclofenac can irritate your stomach and intestine. Taking Hifenac P after food may ease nausea, indigestion and stomach pain. It cannot fully prevent stomach ulcers or gastrointestinal bleeding.
Your risk may be higher if you are older, have had an ulcer, drink alcohol or take blood thinners, steroids or certain antidepressants.
Stop taking the medicine and seek urgent care if you notice black stools, blood in vomit, severe stomach pain, fainting or unusual weakness.
Precautions for Liver, Kidney and Stomach Health
Tell your doctor before taking Hifenac P if you:
- Have active or previous stomach ulcers or digestive bleeding
- Have liver disease
- Have kidney disease
- Have heart disease, high blood pressure, swelling or a previous stroke
- Have asthma triggered by aspirin or another NSAID
- Have a bleeding disorder
- Are dehydrated
- Are pregnant, trying to conceive or breastfeeding
- Are older or have several long-term conditions
Avoid alcohol during treatment. It may increase stomach irritation and add to the risk of liver damage.
Aceclofenac is contraindicated during the third trimester of pregnancy. It should generally be avoided earlier unless your doctor considers it necessary. Ask your doctor before using it while breastfeeding.
Drug Interactions and Contraindications
Hifenac P may interact with:
- Other NSAIDs or paracetamol-containing medicines
- Anticoagulants and antiplatelet medicines
- Corticosteroids
- Certain antidepressants
- Diuretics and some blood pressure medicines
- Lithium
- Methotrexate
- Digoxin
- Ciclosporin or tacrolimus
- Some diabetes medicines
Do not take it if you have had a serious reaction to aceclofenac, paracetamol, aspirin or another NSAID. It may also be unsuitable with active gastrointestinal bleeding, severe liver or kidney failure, or established serious cardiovascular disease.
Monitoring During Treatment
Your doctor may request liver function, kidney function, blood count or blood pressure checks if you need repeated treatment or have relevant risk factors.
Contact your doctor if you develop reduced urination, swelling, yellow skin or eyes, dark urine or unusual tiredness.
Frequently Asked Questions
How Often Can Hifenac P Be Taken in a Day?
Many adult prescriptions use Hifenac P once or twice daily. The right frequency depends on your condition and health. Do not take extra tablets if pain returns before your next dose.
Can Hifenac P Be Taken on an Empty Stomach?
It is better to take it with or just after food. This may reduce digestive discomfort. Food does not remove the possibility of gastrointestinal bleeding.
Is Hifenac P Safe for Long-Term Pain Relief?
Hifenac P is usually intended for the shortest duration needed. Long-term NSAID use can increase gastrointestinal, cardiovascular, liver and kidney risks. Recurring pain needs assessment and a plan that addresses its cause.
Can Hifenac P Damage the Liver or Kidneys?
Serious damage is uncommon with correct short-term use in suitable patients, but it is possible. Paracetamol overdose can injure the liver. Aceclofenac may affect kidney blood flow, especially if you are dehydrated or already have kidney disease.
Does Hifenac P Cause Drowsiness or Dizziness?
Dizziness or drowsiness can occur. Do not drive, operate machinery or perform risky tasks if you feel affected. Speak to your doctor if dizziness is severe or persistent.
Conclusion
Hifenac P Tablet combines aceclofenac and paracetamol to relieve pain and inflammation. Hifenac P Tablet uses include arthritis-related pain, dental pain, back pain and short-term musculoskeletal injuries. Safe use depends on the correct dose, a short treatment duration and attention to stomach, liver, kidney and heart-related risks.
Healthy movement, physiotherapy and treatment of the underlying condition are important when pain keeps returning. Preventive health monitoring can also help you stay informed about key health markers. Metropolis Healthcare offers more than 4,000 tests and full body checkups through NABL and CAP-accredited laboratories. You can access home sample collection through a strong network of 10,000 touchpoints and book through the website, app, call or WhatsApp for accurate results and reliable reports.
References
- Almirall Limited. Preservex 100 mg Film-Coated Tablets: Summary of Product Characteristics. Electronic Medicines Compendium. Updated March 2023.
- Flamingo Pharma UK Ltd. Paracetamol 500 mg Tablets: Summary of Product Characteristics. Electronic Medicines Compendium. Updated September 2025.
- Cao Z, Han K, Lu H, et al. Paracetamol combination therapy for back pain and osteoarthritis: a systematic review and meta-analyses. Drugs. 2024;84(8):953-967. PMID: 38937394.
- Patel PB, Patel TK. Efficacy and safety of aceclofenac in osteoarthritis: a meta-analysis of randomised controlled trials. Eur J Rheumatol. 2017;4(1):11-18. PMID: 28293447.
- Doña I, Jares EJ, Salas M, et al. A review of aceclofenac: analgesic and anti-inflammatory effects on musculoskeletal disorders. J Pain Res. 2021;14:3651-3663. PMID: 34876850.
