Most Recent
Thalassemia and hemoglobinopathies in pediatric populations: Prevalence, Diagnostic Insights, and Regional Patterns
Thalassemia and hemoglobinopathies are inherited disorders affecting the structure or production of hemoglobin, leading to varying degrees of anemia and lifelong health impact. Early detection through advanced screening plays a critical role in prevention, counselling, and improved clinical outcomes. Using high-performance liquid chromatography (HPLC), the study identified notable positivity across all age groups, with the highest incidence in children aged 4–9 years. The findings reinforce the importance of early and systematic screening to detect carriers and affected individuals, especially in regions with higher prevalence.
A Missed Diagnosis or Neglected Parental Premarital Counselling of Rare Case of Compound Heterozygous Sickle Cell-Beta+Thalassemia in Patient: Case Report
Sickle cell disease, an inherited haemoglobin disorder can lead to serious health complications if unrecognized. Prompt diagnosis enables appropriate monitoring, counselling, and preventive care for improved long-term outcomes. This case report highlights a rare instance of compound heterozygous HbS β-thalassaemia, a condition with a very low prevalence. The report emphasizes the difficulty in distinguishing compound haemoglobinopathies from isolated conditions and the importance of accurate diagnosis for optimal management.
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