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Last Updated September 16, 2024
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???? ??? ????-?????? ????????? ????????????? (beta-hCG) ?? ??????????? ?? ????? ???????? ??????? ? (PAPP-A) ?? ???? (PAPP-A) ???? ???? ???

?????? ????? ??? ???? XX ????????? ?? 22 ????? ???? ???, ???? ????? ????? ??? XY ????????? ?? 22 ????? ???? ???? ????????? ????????? ?? ?? ???????????? ??? ?? ?? ?? ????? ????????? ?? ?? ???????? ??? ???? ??? ????????? 21 ?? ?? ????????? ???? ???? ?? ???? ???????? ???? ??, ???? ????????? 21 ?? ??? ???? ??? ?? ????? ??????? ????????? ?????????? ??? ????????? 18 (?? ?????? ?? ???????? ?? ???? ???? ??) ?? ????????? 13 (?? ???? ?? ???????? ?? ???? ???? ??) ?? ?? ????????? ???? ????? ???

??? ???? ??? ?? ?????? (hCG) ?? ???????-? (PAPP-A) ???? ?????????-????????? ??????????? ??? ???????? ????

???????, ??? ?? ???? ??????? ?? ????? ?? ?????? ??? ?????? ????????????? (NT) ????? ???????????? ??? ?? ????? ??? ?? ???? ???? ????? ?? ????? ?? ???? ?? ???????? ???? ?? ????? ???

??????????? ??? ??? ?????? ????? ?? ???????? ?? ???? ???

??????? ?? ???? ?? ??? ??? ?????????? ?? ????? ?? ??? ???? ?????? ?? ????? ????? ?? ????? ?? ???? ?? ???? ??? ????-?????? ????????? ????????????? (free beta-hCG) ?? ??? ??? ??????????? ?? ??????? ??????? ?? ?????????? ????????? (PAPP-A) ?? ????? ???? ???? ???

?? ??? ?? ?????????? ?? ??? ??????? ????? ?? ???? ?? ???? ?? ? ????? ?????? ?? ???? ?? ???? ????? ??? ???? ???? ?????? ????? ?? ??????????? ?? 11??? ?? 14??? ?????? ?? ??? ?? ???? ???

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???????, ??? ????? ?? ???? ???? 35 ???? ?? ???? ??? ?? ???? ????????? ???????????? ?? ??? ??? ???? ?? ??????? ??, ???? ?? ?????? ??? ??? ??? ????????? ?? ????????? ??? ???, ???? ???? ????? ?? ????? ???? ??????

??? ???? ?? ?? ?????? ???? ???? ??? ???? ?? ?? ???? ???? ??? ????????? ?? ???? ????? ??, ?? ????? ???? ????? ?? ?????????? ?? ???? ??? ??????? ??? ?? ??? ???? ??? ??????

?? ?? ?? ???? ??? ?? ??? ?????? ????? ????? ????? ?? ????, ?? ?? ????? ???? ????? ?? ?? ?????? ??? ???? ?????? ???? ??? ???? ?? ???? ???? ??? ?????? ??????? ?? ???? ??? ?? ???? ????? ???? ?? ????? ??? ?? ????? ???? ?? ??? ????? ?????? ??? ???? ??????? ??????????? ?? ???? ??? ??? ????, ?? ???? ???? ???? ????? ????? ?? ??????????? ?? ?????? ?? ??? ??? ??, ?? ???? ?????? ?? ???? ?? ???? ?????? ??? ??????

???? ?????? ?? ??? ??????? ??? ?? ??? ??? ???? ???? ??? ??????? ?? ???? ??? ?? ???? ???????????? ?? ?????? ???????? ?? ?????? ???? ????

??????????? ??? ??? ?????? ????? ???? ???? ???? ???

?? ??? ?????? ????? ??? ???? ?? ????? ???? ???? ?? ?? ?? ???????-????? ???? ???? ??? ???? ???? ?????? (beta hCG) (???? ????????? ?????????????) ?? ???????-? (PAPP-A) ??? ?????? ????? (??????????? ?? ????? ???????? ??????? ?) ??? ???????? ??? ?? ?? ?????? ????

????????? ?????????? ??????? ??? ???? ????-?????? (free beta-hCG) ???? ?????????????? ??????? ?? ????? ???? ??? ?? ??? ?????? ????????? 18 ?? ???? ???????? ?? ????? ????? ?? ????? ??? ???

???????-? (PAPP-A) ???????? ??????? ???? ?? ?? ????? ?????????? ??? ???? ???????? ?? ???? ????? ?? ???????? ??????? ?? ???? ?? ????? ??? ??? ????? ?? ???????? ?? ?????????, ???? ????? ?? ????????? ?? ??? ?? ????? ???? ???

???? ??? ??? ?????? ????? ?? ???? ????? ???

?? ??? ?????? ????? ?? ???? ???? ?????? ?? ????? ?????????? ???? ?????? ?? ???? ?? ???-??? ????? ??????? ?? ?? ????? ?? ????? ???? ????? ?? ?????? ???? ??, ????? ??? ?? ????? ??? ?? ???? ????? ?????????? ?????? ???? ??? ?????? ?? ???? ???

???? ????? ?? ????-?????????? ?????????? ?? ???? ??? ???? ????? ?? ??? ???? ?????????? ????? ?? ?????? ????? ??? ???? ??? ????? ?????????? ???? ??, ?? ?? ??? ?? ??????? ?? ??? ??? ???? ??? ???? ???? ?? ???? ?? ?????? ?????? ?????? ?? ??? ?? ???? ??? ??? ???? ????

??? ?? ???? ???? ?????? ?? ?????????? ????? ??? ?? ???? ???? ?? ???? (NT) ????? ?? ??? ?????? ???? ????, ??????? ?? ?? ??? ?? ?? ??? ??? ???? ???? ??? ?????? ????? ?? ?????? 2,500 ????? ?? 3,500 ????? ?? ??? ???? ???, ?? ?? ??? ?? ?????? ???? ?? ?? ?? ???? ???? ??? ?? ?? ???-?? ??????? ????? ????

????? ???????? ?? ???? ?????? ?????

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??? ??? ???? ???? ??? ??? ?? ???? ??? ????? ?? ?????? ??? ?? ??? 3 ?? 7 ????? ?? ??? ??? ?? ?? ????? ??????? ?? ???? ??????? ???? ???????? ?? ??? ??? ????? ?? ???? ???? ???? ?????? ???? ?? ???????? ???

????? ???? ???? ???? ??????

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?: ?? ?????? ?? ???????? ???? ???? ????? ??? ???? ?? ?????? ?? ??????? ?? ?????? ????? ?? ???? ??? ??? ????? ?? ??? ?????? ????? ??????? ?????? ?? ?????? ???, ?????? ?????? ?? ?? ?? ??? ????? ?? ??? ?? ????? ??????? ??????????? ???? ?????????????? (amniocentesis) ?? ????????? ???? (chorionic villus) ?????? ???? ?? ???? ?? ???? ????

??????: ??????????? ??? ??? ?????? ????? ?? ??? ?? ??????? ???? ???? ???? ???? ???

?: ?? ??? ?????? ????? ?? ?? ??????? ???? 25,700 ?? 2,88,000 mIU ????? mL ???

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