??????? ???????????? 7 ?? 9 ???? ??????????? ?????, ?????? ???????? ????????? ?????? ?????? ??????? ??? ?????. ??? ?????? ??????? ???????? ?????? ???? ??? ??? ??????? ?????? ?? ????? ???? ?????, ????? ??????????????? ????? ???????? ??????? ???? ???????????? ?????????? ????? ?????? ???? ??????? ?????? ???????.
??? ?????? ?????????? ????? ????? ???????? ?????????? ?? ???? ????? ????? ?? ???? ????? ?????????? ??????? ??????? ????? ????? ????.
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???????????? 1 ?? 3 ???? ??????????? ???????????? ??? ?????? ????? ???? ????, ?? ??????? ??????? ???? ?????????? ????? ???????. ???? ?? ????? ??????????? ???????? ????? ????, ??? ???????????? ?????????? ?????? ?????? ?????? ????. ?? ????? ???????? ????? ???? ???? ????? ????????? ????? ???.
???????? ???? ????-?????? ?????????? ????????????? (free beta-hCG) ??? ?????????????? ???????? ??????? ? (PAPP-A) ????? ???? ????? ?????.
???????? ??? ?? ????? ???? ?? ????????????? XX ?????????????? 22 ?????? ??????, ???????????? ?? ??? ????? ???? ?? XY ?????????????? 22 ?????? ??????. ???????? ?????????????? ??????????? ??????? ?????? ???????????? ??????? ?????? ?????????. ???????? 21 ?? ???????? ???? ?????????? ???? ???????? ????, ?????? ????????? 21 ??? ????? ???????. ???????? 18 ???????? ???????? ???????? ????) ????? ???????? 13 (???????? ???? ???????? ????) ??????????? ????? ????? ???????? ???? ????? ????, ?? ????? ?? ???????? ??????? ???????? ???????? ????.
???????? ??????? ???????? ???? ???????????? ????? ????? hCG ??? PAPP-A ???? ???????? ???????? ???? ?????? ????.
??? ???????? ?? ???????? ?? ??? ???? ???, ?????? ?????????????? (NT) ??????? ?? ?????????? ?????????????? ????? ????????? ?????????????? ??????? ???????? ???????? ?????? ???????? ??????? ???????? ???? ????.
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????????????? ?? ????? ??????? ??? ????????? ?????? ???????? ???? ???????? ????????????? ??? ??? ???????? ????? ??????? ??? ?????. ?? ??????? ?????????? ?????????????? ???????? ????-?????? ?????????? ????????????? (???? beta-hCG) ??? ???????? ?????? ????????? ????? ???? ???? (PAPP-A).
?? ?????????? ???????? ???? ??????????? ??? ??? ??????? ?????? ????. ?????? ????? ???? ?????? ????? ????? ??? ?????. ?? ???????????? ????????? ???????????? 11 ???? ??? 14 ???? ???????? ???? ????.
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???????????? ??????? ??? ????????? ??? ?????? ????? ??? NT ?? ?????????? ?????? ???? ????? ?? ???????? ????.
?????, ???? ????? ?? 35 ?????? ????? ??? ????? ???????? ??????? ???????? ????? ????? ????, ??? ?? ???? ??? ?????? ??????? ????? ???????? ?????? ????????. ??? ??????????, ?????? ?? ?????????? ???? ???? ????????? ????.
?????? ??? ???? ?? ?? ???????? ?????? ???????? ???????????? ?? ????? ???? ???? ?? ????????? ????? ?????. ?? ?????? ?????? ???. ??????? ?????? ???? ?? ????????? ???????? ????????? ??????? ?????????? ???????? ??? ??? ????.
?????? ?????? ????? ?? ??? ?????? ????? ?????? ?? ????, ?????? ?? ?????? ???? ?????? ?????????? ???? ?? ?? ????????? ?????????? ???????? ????????? ??? ?????? ????? ???. ?? ?????? ????????????? ????? ????? ??? ?????? ????? ??????? ?????????????? ???? ??? ???????? ???? ?? ???? ??????? ?????????????? ????? ?? ???????? ??? ?????? ?????? ?????? ??????????? ??????? ????, ?????? ?????????? ????? ????????? ????? ???
??????? ?????? ??????? ??????? ??? ????? ???? ???? ?? ???????? ??????? ?????????? ??????????? ??? ?????? ?????????? ??????? ????.
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??? ?????? ?????????? ??????? ????? ???? ??? ?????? ?????????????? (NT) ??????? ?????? ????. ???? beta-hCG (????-?????? ?????????? ?????????????) ??? PAPP-A ?? ??? ???????? ??? ?????? ????? ??????? ?????? ?????. (?????????????? ???????? ??????? A).
????? ??????????? ????????? ???? beta-hCG ?????? ?? ??????? ?????????????? ??????? ?????. ?? ?? ????? ???????? ????? ???? ?? ????????? 18 ??? ???? ?????????? ???? ?????.
PAPP-A ???????? ??????? ?? ???????? ?? ?????????? ??? ???. ???? ?????????? ???? ????? ???????? ???? ??? ?? ???????? ????????? ???? ??? ???? ???. ?? ??????? ?????? ?????????, ???? ????? ????, ????? ????????? ??? ??? ?????.
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??? ?????? ??????? ???? ????? ?????? ??? ????? ????????? ????????? ?????. ??? ?? ????? ???? ???? ??????????? ???????? ????, ??? ?????? ????? ???? ?? ??????? ????? ????????? ????? ????? ?? ???? ????? ???? ????.
??????? ??????? ??? ????? ????????? ?????? ????????? ?????? ???? ?????????? ??????? ????????? ??????? ?????? ???. ?? ????? ????? ????????? ????, ??? ?????? ???????? ????? ??????????? ??? ?????? ???? ???? ??? ???????? ???????? ?????? ?????? ???? ?? ????? ??? ????.
???????? ?? ??????? ??? ??????????? ?????????? ???? ??????? ???? ?? ?????? ??? NT ????????? ???? ????? ??????, ???? ?? ?????? ??????? ?????? ?????? ?????. ??? ?????? ??????? ???? ?????? 2,500 ??. ????? 3,500 ??. ??????? ??? ????, ?? ???? ?????? ???? ????? ??? ?????? ????? ???????? ?????? ??? ???? ??????? ????.
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??? ?????? ????????? ???? ???? ?????? ???? ????. ??????????? ???????? ???? ??????? ?????????? ?? ????? ???? ???????? ?????????? ?? ?????? ??? ????? ?????. ???? ????? ????? ????? ??, ?????? ???????????? ????-???? ?? ????? ??? ????, ???? ?? ??????? ?????????? ????? ????.
?????? ???????? ???????? ???????????? ??????? ?????????? ??? ????. ????????????? ?? ??????? ?????? 3 ?? 7 ???????? ??????. ??????? ???? ???????? ??? ???? ?????? ????? ????? ????? ???????? ??????? ??? ?????? ?????? ??? ?? ???????? ??????? ?????? ?????.
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?? ?????? ???? ???????? ?????? ??????? ???? ???????? ?????? ?????? ????. ?? ??? ?????? ????? ????????? ???, ?? ???? ?????????? ?? ??????????????? ???? ????? ?????????? ?????? ???????? ????? ????????? ???? ?? ??????????????? ????? ?????????? ?????? ??????? ???????? ????? ?????.
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??? ?????? ??????? ??????? ????? 25,700 ?? 2,88,000 mIU ????? mL ?????.
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??? ?????? ????? ?? ???? ?? ????? ????. ???????? ??? ??? ????????? ???? ??????! ??????? ????? ?????, ?? ??????? ?????? ?????? ??? ?????. ?? ????????? ?????????? ?????? ?????????? ??????????????? ????? ???? ???? ?????? ????.